PABPC1

Gene Symbol PABPC1
Entrez Gene 26986
Alt Symbol PAB1, PABP, PABP1, PABPC2, PABPL1
Species Human
Gene Type protein-coding
Description poly(A) binding protein, cytoplasmic 1
Other Description poly(A) binding protein, cytoplasmic 2|polyadenylate-binding protein 1
Swissprots Q15097 Q93004 P11940
Accessions AAD08718 CBX53830 EAW91814 EAW91815 EAW91816 EAW91817 EAW91818 EAW91819 EAW91820 EAW91821 P11940 AK095194 BAG53005 AK130523 AK298990 BAG61082 AK303120 BAG64226 AL135187 BC015958 AAH15958 BC023217 BC023520 AAH23520 BC041863 DQ893508 ABM84434 DQ896500 ABM87499 KC832802 Y00345 CAA68428 Z48501 CAA88401 XM_005250861 XP_005250918 NM_002568 NP_002559
Function Binds the poly(A) tail of mRNA, including that of its own transcript. May be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. Involved in translationally coupled mRNA turnover. Implicated with other RNA- binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding- region determinant of instability (mCRD) domain. Involved in regulation of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons; for the recognition of premature termination codons (PTC) and initiation of NMD a competitive interaction between UPF1 and PABPC1 with the ribosome-bound release factors is proposed. {ECO:0000269|PubMed:11051545, ECO:0000269|PubMed:17212783, ECO:0000269|PubMed:18447585, ECO:0000269|PubMed:2057
Subcellular Location Cytoplasm. Nucleus. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Shuttles between the cytoplasm and the nucleus.
Tissue Specificity Ubiquitous.
Top Pathways RNA degradation, RNA transport, mRNA surveillance pathway

Polyadenylate-binding protein 1, ELISA Kit - MBS282270 from MyBioSource

Category ELISA Kit
Prices $425.00, $720.00, $3,160.00, $6,055.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human PABPC1 ELISA Kit - E030037 from Biobool

Category ELISA Kit

anti-PABPC1 antibody - ARG66214 from Arigo Biolaboratories

Category ELISA Kit

Polyadenylate-Binding Protein 1 (PABP1), ELISA Kit - MBS9393802 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Polyadenylate-Binding Protein 1 (PABP1), ELISA Kit - MBS9393810 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Polyadenylate-Binding Protein 1 (PABP1), ELISA Kit - MBS9393795 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Polyadenylate-Binding Protein 1 (PABP1), ELISA Kit - MBS9393798 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Polyadenylate-Binding Protein 1 (PABP1), ELISA Kit - MBS9393796 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Polyadenylate-Binding Protein 1 (PABP1), ELISA Kit - MBS9393797 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Polyadenylate-Binding Protein 1 (PABP1), ELISA Kit - MBS9393801 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Polyadenylate-Binding Protein 1 (PABP1), ELISA Kit - MBS9393806 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Polyadenylate-Binding Protein 1 (PABP1), ELISA Kit - MBS9393799 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Polyadenylate-Binding Protein 1 (PABP1), ELISA Kit - MBS9393803 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Polyadenylate-Binding Protein 1 (PABP1), ELISA Kit - MBS9393805 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Polyadenylate-Binding Protein 1 (PABP1), ELISA Kit - MBS9393804 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Polyadenylate-Binding Protein 1 (PABP1), ELISA Kit - MBS9393800 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Polyadenylate-Binding Protein 1 (PABP1), ELISA Kit - MBS9393807 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Polyadenylate-Binding Protein 1 (PABP1), ELISA Kit - MBS9393808 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Polyadenylate-Binding Protein 1 (PABP1), ELISA Kit - MBS9393809 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Polyadenylate-Binding Protein 1 (PABP1), ELISA Kit - MBS9393811 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Polyadenylate-Binding Protein 1 (PABP1), ELISA Kit - MBS9393812 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Polyadenylate-Binding Protein 1 (PABP1), ELISA Kit - MBS9393813 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Polyadenylate-Binding Protein 1 (PABP1), ELISA Kit - MBS9393814 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

SimpleChIP ® Human PabPC1 Exon 1 Primers - 77410 from Cell Signaling Technology

Category ChIP Kit
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