CBX7

Gene Symbol CBX7
Entrez Gene 23492
Alt Symbol -
Species Human
Gene Type protein-coding
Description chromobox homolog 7
Other Description chromobox protein homolog 7
Swissprots O95931 Q86T17
Accessions EAW60297 EAW60298 EAW60299 EAW60300 EAW60301 O95931 AK124408 BC051773 AAH51773 BC128418 DQ064603 AAY68391 EU446785 ABZ92314 XM_005261413 XP_005261470 XM_006724174 XP_006724237 XM_006724175 XP_006724238 XM_006724176 XP_006724239 XM_006724177 XP_006724240 XM_006724178 XP_006724241 XM_011530025 XP_011528327 NM_175709 NP_783640
Function Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity. {ECO:0000269|PubMed:19636380, ECO:0000269|PubMed:21047797, ECO:0000269|PubMed:21060834, ECO:0000269|PubMed:21282530}.
Subcellular Location Nucleus {ECO:0000269|PubMed:14647293, ECO:0000269|PubMed:21060834, ECO:0000269|PubMed:21282530}.

CBX7 (T-17) - sc-70234 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

CBX7 (P-15) - sc-70232 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CBX7 (P-15): sc-70232. Western blot analysis of CBX7 expression in SK-N-MC nuclear extract.

CBX7 (S-14) - sc-70233 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CBX7 (S-14): sc-70233. Immunofluorescence staining of methanol-fixed NIH/3T3 cells showing nuclear localization.

Anti-cbx7 antibody - ab89637 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-cbx7 antibody (ab89637) at 1 µg/ml + HeLa nuclear extract at 50 µg

Anti-cbx7 antibody [EPR12630] - ab178411 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12630
Flow Cytometrical analysis of permeabilized HeLa cells labeling cbx7 with ab178411 at 1/10 (red) compared to a nonspecific negative control antibody (green).

Anti-CBX7 Antibody (aa88-99) - LS-C204981 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-CBX7 Antibody - LS-C306756 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-CBX7 Antibody (C-Terminus) - LS-C109917 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CBX7 antibody LS-C109917 Western blot of HepG2 cell lysate.

Anti-CBX7 Antibody - LS-C155433 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate) A: HeLa 12% SDS PAGE CBX7 antibody diluted at 1:1000

Anti-CBX7 Antibody (aa201-251) - LS-C286900 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human CBX7 by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-CBX7 used at a dilution of 1:250.

Anti-CBX7 Antibody (aa144-178) - LS-C344636 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysates from HeLa cell line, mouse brain, mouse testis, mouse lung, mouse spleen, rat brain tissue (from left to right) with Mouse Cbx7 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20 ug per lane.

Anti-CBX7 Antibody (aa201-251) - LS-C289258 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human CBX7 by Immunohistochemistry. Sample: FFPE section of human lung carcinoma. Antibody: Affinity purified rabbit anti-CBX7 used at a dilution of 1:200 (1 ug/ml).

CBX7 Antibody - NBP1-40343 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CBX7 Antibody [NBP1-40343] - Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 mcg) cells. Affinity purified rabbit anti-CBX7 antibody used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 10 mcg/mg lysate

CBX7 Antibody - NBP2-38793 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: CBX7 Antibody [NBP2-38793] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.

CBX7 Antibody - H00023492-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: CBX7 Antibody [H00023492-B01P] - Analysis of CBX7 expression in Hela S3 NE.

CBX7 Antibody - NBP1-79042 from Novus Biologicals

Host Rabbit
Clonality Polyclonal
Immunohistochemistry: CBX7 Antibody [NBP1-79042]-FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-CBX7 used at a dilution of 1:250

CBX7 Antibody - NBP2-38585 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: CBX7 Antibody [NBP2-38585] - Staining of human kidney shows strong cytoplasmic and nuclear positivity in cells in tubules.

CBX7 Antibody - NBP2-15737 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CBX7 Antibody [NBP2-15737] - Sample (30 ug of whole cell lysate) A: HeLa 12% SDS PAGE gel, diluted at 1:1000.

Anti-CBX7 antibody produced in rabbit - SAB2100347 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CBX7: <B>Cat. No.SAB2100347</B>: CBX7 in HepG2 cell lysate with CBX7 antibody at 1.0 μg/mL.

Anti-CBX7 (197-209) antibody produced in rabbit - SAB1101723 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-CBX7 (197-209) (RB): <B>Cat. No. SAB1101723</B>: Immunofluorescence of HUVEC cells using Anti-CBX7 (197-209) (RB) at a 1:100 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-CBX7 antibody produced in mouse - SAB1407218 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CBX7: <B>Cat. No. SAB1407218</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~28.3 kDa using HeLa NE lysate.

CBX7 antibody - middle region (ARP34493_P050) - ARP34493_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CBX7 Antibody - C-terminal region (ARP74429_P050) - ARP74429_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CBX7-aa88-99-Antibody-internal-region - AF3847a from Abgent, a WuXi AppTec company

Prices $325.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

CBX7-Antibody-C-term - AP21163a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CBX7 Antibody (C-term) at 1:1000 dilution + HepG2 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 28 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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