CBX7

Gene Symbol CBX7
Entrez Gene 23492
Alt Symbol -
Species Human
Gene Type protein-coding
Description chromobox homolog 7
Other Description chromobox protein homolog 7
Swissprots O95931 Q86T17
Accessions EAW60297 EAW60298 EAW60299 EAW60300 EAW60301 O95931 AK124408 BC051773 AAH51773 BC128418 DQ064603 AAY68391 EU446785 ABZ92314 XM_005261413 XP_005261470 XM_006724174 XP_006724237 XM_006724175 XP_006724238 XM_006724176 XP_006724239 XM_006724177 XP_006724240 XM_006724178 XP_006724241 XM_011530025 XP_011528327 NM_175709 NP_783640
Function Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity. {ECO:0000269|PubMed:19636380, ECO:0000269|PubMed:21047797, ECO:0000269|PubMed:21060834, ECO:0000269|PubMed:21282530}.
Subcellular Location Nucleus {ECO:0000269|PubMed:14647293, ECO:0000269|PubMed:21060834, ECO:0000269|PubMed:21282530}.

CBX7Over-expression-Lysate - LY15651a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag CBX7 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 2) or transiently transfected with theCBX7 gene

CBX7 293T Cell Transient Overexpression Lysate(Denatured) - H00023492-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

CBX7 293 Cell Lysate - 403863 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

CBX7 Overexpression Lysate (Denatured) - H00023492-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

CBX7 Overexpression Lysate (Native) - NBL1-08752 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg

CBX7 Over-expression Lysate Product - GWB-F39E3A from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

CBX7 Overexpression Lysate (Denatured) - H00023492-T02 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl

Panoply™ Human CBX7 Knockdown Stable Cell Line - CSC-DC002442 from Creative biogene

Category Cell Line
Species Human
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