Gene Symbol | CBX7 |
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Entrez Gene | 23492 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | chromobox homolog 7 |
Other Description | chromobox protein homolog 7 |
Swissprots | O95931 Q86T17 |
Accessions | EAW60297 EAW60298 EAW60299 EAW60300 EAW60301 O95931 AK124408 BC051773 AAH51773 BC128418 DQ064603 AAY68391 EU446785 ABZ92314 XM_005261413 XP_005261470 XM_006724174 XP_006724237 XM_006724175 XP_006724238 XM_006724176 XP_006724239 XM_006724177 XP_006724240 XM_006724178 XP_006724241 XM_011530025 XP_011528327 NM_175709 NP_783640 |
Function | Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity. {ECO:0000269|PubMed:19636380, ECO:0000269|PubMed:21047797, ECO:0000269|PubMed:21060834, ECO:0000269|PubMed:21282530}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:14647293, ECO:0000269|PubMed:21060834, ECO:0000269|PubMed:21282530}. |
Human cbx7 full length protein - ab132078 from Abcam
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Human cbx7 peptide - ab22423 from Abcam
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Human cbx7 peptide - ab22424 from Abcam
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Human cbx7 protein fragment - ab198427 from Abcam
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CBX7 Antibody Blocking Peptide - LS-E12231 from LifeSpan Bioscience
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Recombinant Human CBX7 Protein - H00023492-P01 from Novus Biologicals
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CBX7 Protein Lysate (APL10826) - APL10826 from Aviva Systems Biology
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Human CBX7 protein - orb244075 from Biorbyt
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Human CBX7 protein - orb245779 from Biorbyt
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CBX7 - H00023492-P01-10 from Acris Antibodies
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CBX7 - H00023492-P01-25 from Acris Antibodies
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CBX7 fusion protein - ag7178 from Proteintech Group
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Recombinant Human CBX7, His-tagged - CBX7-10772H from Creative Biomart
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Recombinant Human Chromobox protein homolog 7(CBX7) - CSB-YP004603HU CSB-BP004603HU CSB-MP004603HU from Cusabio
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Recombinant Human Chromobox protein homolog 7(CBX7) - CSB-EP004603HU from Cusabio
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CBX7 fusion protein - Ag24588 from Proteintech Group
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CBX7, Peptide - MBS428223 from MyBioSource
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CBX7 Recombinant Protein Antigen - NBP2-38793PEP from Novus Biologicals
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CBX7 Recombinant Protein Antigen - NBP2-38585PEP from Novus Biologicals
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CBX7 Protein Lysate - orb333536 from Biorbyt
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CBX7-Blocking-Peptide-C-term - BP21163a from Abgent, a WuXi AppTec company
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CBX7 Peptide, Human - M34GP02442H from Creative Peptides
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Recombinant Human Chromobox protein homolog 7 - AP70125 from Signalway Antibody
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Recombinant Human Chromobox protein homolog 7 - AP72480 from Signalway Antibody
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Chromobox protein homolog 7, Recombinant Protein - MBS9420076 from MyBioSource
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