GLRX3

Gene Symbol	GLRX3
Entrez Gene	10539
Alt Symbol	GLRX4, GRX3, GRX4, PICOT, TXNL2, TXNL3
Species	Human
Gene Type	protein-coding
Description	glutaredoxin 3
Other Description	PKC-interacting cousin of thioredoxin|PKC-theta-interacting protein|PKCq-interacting protein|glutaredoxin 4|glutaredoxin-3|thioredoxin-like protein 2
Swissprots	B3KMQ5 B3KMP7 O76003 Q9P1B0 Q96CE0 D3DRG2 Q5JV01 Q9P1B1
Accessions	EAW49152 EAW49153 EAW49154 EAW49155 O76003 AA995117 AF118649 AAF28841 AF118652 AAF28844 AJ010841 CAA09375 AK022131 BAG51067 AK225609 BC005289 AAH05289 BC014372 AAH14372 BI256922 BP347054 XM_005252657 XP_005252714 NM_001199868 NP_001186797 NM_006541 NP_006532
Function	Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). Crucial regulator of cellular iron homeostasis and hemoglobin maturation. May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity. {ECO:0000250, ECO:0000269|PubMed:23615448}.
Subcellular Location	Cytoplasm, cell cortex {ECO:0000269|PubMed:10636891}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250}. Note=Under the plasma membrane. After PMA stimulation, GLRX3 and PRKCQ/PKC-theta translocate to a more extended submembrane area. In the Z line, found associated with CSRP3 (By similarity). {ECO:0000250}.
Tissue Specificity	Expressed in heart, spleen, testis and, to a lower extent, in thymus and peripheral blood leukocytes. Weakly expressed in lung, placenta, colon and small intestine.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TXNL2 full length protein - ab95263 from Abcam Category Protein Source E. coli Species Human

Human TXNL2 full length protein - ab169921 from Abcam Category Protein Source E. coli Species Human

GLRX3 / Glutaredoxin 3 Antibody Blocking Peptide - LS-E1426 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GLRX3 / Glutaredoxin 3 Antibody Blocking Peptide - LS-E21461 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TXNL2 Recombinant Protein - H00010539-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human TXNL2 Protein - NBP1-44478 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

TXNL2-Antibody-N-term-Blocking-peptide - BP12099a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GLRX3 Protein (OPPA02033) - OPPA02033 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

GLRX3 Blocking Peptide - 33R-5905 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human Glutaredoxin 3 Protein - abx066826 from Abbexa Category Protein Source E.coli Species Human

Human Glutaredoxin 3 Protein - abx066825 from Abbexa Category Protein Source E.coli Species Human

Glutaredoxin-3 / GLRX3 (1-335, His-tag) - AR09461PU-L from Acris Antibodies Category Protein Prices $695.00 Sizes 500 µg Source E. coli Species Human

Glutaredoxin-3 / GLRX3 (1-335, His-tag) - AR09461PU-N from Acris Antibodies Category Protein Prices $305.00 Sizes 100 µg Source E. coli Species Human

Glutaredoxin-3 / GLRX3 - H00010539-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Glutaredoxin-3 / GLRX3 - H00010539-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Glutaredoxin-3, Human Recombinant - 228-12500-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Human Glutaredoxin-3 - 228-12500-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human Glutaredoxin-3 - 228-12500-3 from RayBiotech Category Protein Prices $2,400.00 Sizes 3 µg Source Escherichia Coli. Species Human

Glutaredoxin 3 (GLRX3), Human - 20-9218 from ARP American Research Products Category Protein Prices $369.00 Sizes 50 µg Source E.coli Species Human

Glutaredoxin 3 (GLRX3), Human - 20-9219 from ARP American Research Products Category Protein Prices $369.00 Sizes 50 µg Source E.coli Species Human

Glutaredoxin-3, 1-335aa, Human, His tag, E.coli - 01-2024-3 from ARP American Research Products Category Protein Prices $159.00, $339.00, $749.00 Sizes 20 µg, 100 µg, 500 µg Species Human

GLRX3 fusion protein - Ag1775 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

GLRX3 Human - ENPS-489 from NeoScientific Category Protein Prices $65.00, $169.00, $2,925.00 Sizes 5 µg, 25 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human Glutaredoxin-3 - BP000610-ENZ-482 from Syd Labs Category Protein Prices $160.00, $2,250.00 Sizes 25 µg, 1 mg Source E. coli-derived. Species Human

Glutaredoxin-3, 1-335aa, Recombinant Protein - GWB-P1487E from Genway Biotech Category Protein Prices $260.00, $780.00 Sizes 100 μg, 500 μg Source E.coli Species Human

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