METAP2

Gene Symbol METAP2
Entrez Gene 10988
Alt Symbol MAP2, MNPEP, p67, p67eIF2
Species Human
Gene Type protein-coding
Description methionyl aminopeptidase 2
Other Description MAP 2|eIF-2-associated p67 homolog|initiation factor 2-associated 67 kDa glycoprotein|metAP 2|methionine aminopeptidase 2|p67|p67eIF2|peptidase M 2
Swissprots Q8NB11 G3XA91 B2RDI8 P50579 B4DUX5
Accessions CCO13769 EAW97537 EAW97538 EAW97539 P50579 AK055692 AK091730 BAC03733 AK125296 BAG54178 AK300836 BAG62487 AK315559 BAG37935 BC013782 AAH13782 BC016008 AAH16008 DQ891013 ABM81939 DQ894193 ABM85119 DW409106 U13261 AAC63402 XM_005268583 XP_005268640 NM_006838 NP_006829
Function Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N- terminal Met-Val and Met-Thr sequences in vivo.
Subcellular Location Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03175, ECO:0000269|PubMed:21537465}. Note=About 30% of expressed METAP2 associates with polysomes.

Human METAP2 cDNA clone(NM_006838.3) - CDFH011360 from Creative Biomart

Species Human
Accession NM_006838.3

Human METAP2 ORF clone(NM_006838.3) - CDCL185329 from Creative Biomart

Species Human
Accession NM_006838.3

Human METAP2 ORF Clone(NM_006838.3) - CDCR293789 from Creative Biomart

Species Human
Accession NM_006838.3

Human METAP2 ORF Clone(NM_006838.3) - CDCR293790 from Creative Biomart

Species Human
Accession NM_006838.3

Human METAP2 ORF Clone(NM_006838.3) - CDCL169960 from Creative Biomart

Species Human
Accession NM_006838.3

Human METAP2 ORF clone(NM_006838.3) - CDCL185329 from Creative biogene

Species Human

Human METAP2 gene - orb90837 from Biorbyt

Prices $264.00
Sizes 10 μg
Species Human

Human METAP2 cDNA Clone(NM_006838.3) - CDFH011360 from Creative biogene

Species Human
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