METAP2

Gene Symbol	METAP2
Entrez Gene	10988
Alt Symbol	MAP2, MNPEP, p67, p67eIF2
Species	Human
Gene Type	protein-coding
Description	methionyl aminopeptidase 2
Other Description	MAP 2|eIF-2-associated p67 homolog|initiation factor 2-associated 67 kDa glycoprotein|metAP 2|methionine aminopeptidase 2|p67|p67eIF2|peptidase M 2
Swissprots	Q8NB11 G3XA91 B2RDI8 P50579 B4DUX5
Accessions	CCO13769 EAW97537 EAW97538 EAW97539 P50579 AK055692 AK091730 BAC03733 AK125296 BAG54178 AK300836 BAG62487 AK315559 BAG37935 BC013782 AAH13782 BC016008 AAH16008 DQ891013 ABM81939 DQ894193 ABM85119 DW409106 U13261 AAC63402 XM_005268583 XP_005268640 NM_006838 NP_006829
Function	Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N- terminal Met-Val and Met-Thr sequences in vivo.
Subcellular Location	Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03175, ECO:0000269|PubMed:21537465}. Note=About 30% of expressed METAP2 associates with polysomes.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Methionine Aminopeptidase 2 full length protein - ab153147 from Abcam Category Protein Source Wheat germ Species Human

Human Methionine Aminopeptidase 2 full length protein - ab168057 from Abcam Category Protein Source Insect cells Species Human

METAP2 Antibody Blocking Peptide - LS-E3240 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

METAP2 Antibody Blocking Peptide - LS-E18780 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

METAP2 Antibody Blocking Peptide - LS-E6944 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

METAP2 Antibody Blocking Peptide - LS-E6945 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Methionine Aminopeptidase 2/METAP2 Peptide - P1067 from Novus Biologicals Category Peptide Species Human

Methionine Aminopeptidase 2/METAP2 Peptide - P1066 from Novus Biologicals Category Peptide Species Human

METAP2-Antibody-N-term-Blocking-Peptide - BP14389a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

METAP2-Antibody-N-term-Blocking-Peptide - BP2320a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Methionine-Aminopeptidase-2-METAP2-Antibody-C-term-Blocking-peptide - BP2320b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Methionine Aminopeptidase 2, CF - 3795-ZN-020 from R&D Systems Category Protein Source Spodoptera frugiperda, Sf 21 (baculovirus)-derived, Ala2-Tyr478, with a C-terminal 10-His tag

Recombinant human Methionine aminopeptidase 2 (OPCA00159) - OPCA00159 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Recombinant human Methionine aminopeptidase 2 (OPCA01273) - OPCA01273 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Human METAP2 protein - orb244372 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human METAP2 protein - orb245918 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human METAP2 (His Tag) protein - orb232221 from Biorbyt Category Protein Prices $510.00, $1,088.00 Sizes 20 μg, 100 μg Species Human

METAP2 Blocking Peptide - 33R-1556 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

METAP2 - H00010988-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

METAP2 - H00010988-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

METAP2 fusion protein - ag10655 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

METAP2 fusion protein - ag10564 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human METAP2, His-tagged - METAP2-635H from Creative Biomart Category Protein Source Spodoptera frugiperda

Recombinant Human Methionyl Aminopeptidase 2, GST-tagged - METAP2-630H from Creative Biomart Category Protein Source Insect cells .

Recombinant Methionyl Aminopeptidase 2 (METAP2) - RPH663Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

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