GBP1

Gene Symbol GBP1
Entrez Gene 2633
Alt Symbol -
Species Human
Gene Type protein-coding
Description guanylate binding protein 1, interferon-inducible
Other Description GBP-1|GTP-binding protein 1|guanine nucleotide-binding protein 1|guanylate binding protein 1, interferon-inducible, 67kDa|huGBP-1|interferon-induced guanylate-binding protein 1
Swissprots Q5T8M1 D3DT26 P32455
Accessions EAW73148 EAW73149 EAW73150 P32455 AB208912 BAD92149 AK291783 BAF84472 AK298032 BAG60334 AK303893 BAG64827 AY920436 AAX13805 BC002666 AAH02666 BF058809 BT006847 AAP35493 CB164272 CD676970 DQ890759 ABM81685 DQ893924 ABM84850 M55542 AAA35871 XM_006710573 XP_006710636 NM_002053 NP_002044
Function Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes. {ECO:0000269|PubMed:22106366}.
Subcellular Location Cytoplasm. Golgi apparatus membrane; Lipid- anchor; Cytoplasmic side. Secreted. Note=Secreted from endothelial cells in the cerebrospinal fluid, upon bacterial challenge and independently of interferon-gamma induction. Golgi membrane localization requires isoprenylation and the presence of another IFN-gamma-induced factor.

GBP1-Over-expression-Lysate - LY12704a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag GBP1 (arrow) using his tag antibody. 293T cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the GBP1 gene

GBP1 293T Cell Transient Overexpression Lysate(Denatured) - H00002633-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

GBP1 293 Cell Lysate - 400723 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

GBP1 Overexpression Lysate (Native) - NBL1-10996 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: GBP1 Overexpression Lysate (Adult Normal) [NBL1-10996] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GBP1.

GBP1 Over-expression Lysate Product - GWB-154636 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Human GBP1 HEK293 Cell Lysate (WB positive control) - 12569-H08HL-300 from Sino Biological

Category Cell Lysate
Prices $195.00
Sizes 300 µg
Species Human

Human GBP1 Human Cells Transfected Lysate (positive control) (denatured) - orb179412 from Biorbyt

Category Cell Lysate
Prices $425.00
Sizes 300 μg
Species Human

GBP1 Overexpression Lysate (Denatured) - H00002633-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Panoply™ Human GBP1 Knockdown Stable Cell Line - CSC-DC006142 from Creative biogene

Category Cell Line
Species Human
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