Gene Symbol | GBP1 |
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Entrez Gene | 2633 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | guanylate binding protein 1, interferon-inducible |
Other Description | GBP-1|GTP-binding protein 1|guanine nucleotide-binding protein 1|guanylate binding protein 1, interferon-inducible, 67kDa|huGBP-1|interferon-induced guanylate-binding protein 1 |
Swissprots | Q5T8M1 D3DT26 P32455 |
Accessions | EAW73148 EAW73149 EAW73150 P32455 AB208912 BAD92149 AK291783 BAF84472 AK298032 BAG60334 AK303893 BAG64827 AY920436 AAX13805 BC002666 AAH02666 BF058809 BT006847 AAP35493 CB164272 CD676970 DQ890759 ABM81685 DQ893924 ABM84850 M55542 AAA35871 XM_006710573 XP_006710636 NM_002053 NP_002044 |
Function | Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes. {ECO:0000269|PubMed:22106366}. |
Subcellular Location | Cytoplasm. Golgi apparatus membrane; Lipid- anchor; Cytoplasmic side. Secreted. Note=Secreted from endothelial cells in the cerebrospinal fluid, upon bacterial challenge and independently of interferon-gamma induction. Golgi membrane localization requires isoprenylation and the presence of another IFN-gamma-induced factor. |
Human GBP1 full length protein - ab114960 from Abcam
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GBP1 Antibody Blocking Peptide - LS-E1715 from LifeSpan Bioscience
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Recombinant Human GBP1 Protein - H00002633-P01 from Novus Biologicals
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GBP1-Antibody-N-term-Blocking-peptide - BP12492a from Abgent, a WuXi AppTec company
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Human GBP1 protein (His Tag) - orb138907 from Biorbyt
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GTP-binding protein 1 / GBP1 - H00002633-P01-10 from Acris Antibodies
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GTP-binding protein 1 / GBP1 - H00002633-P01-25 from Acris Antibodies
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GBP1 fusion protein - Ag7562 from Proteintech Group
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GBP1 fusion protein - Ag7767 from Proteintech Group
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Recombinant Human GBP1 - GBP1-28991TH from Creative Biomart
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Recombinant Human GBP1, His tagged - GBP1-6940H from Creative Biomart
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Recombinant Human GBP1, GST-tagged - GBP1-13180H from Creative Biomart
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Human GBP1 Protein (His Tag) - 12569-H08H-20 from Sino Biological
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GBP1 (E99) Peptide - BS3028P from Bioworld Technology
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Recombinant Human Interferon-induced guanylate-binding protein 1(GBP1) - CSB-YP009297HU CSB-EP009297HU CSB-BP009297HU CSB-MP009297HU from Cusabio
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GBP1 Blocking Peptide - abx161628 from Abbexa
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GTP-binding protein 1 / GBP1 - TP301236 from Acris Antibodies
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Recombinant Human GBP1 Protein (His tag) - PKSH030815 from Elabscience
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Recombinant Human GBP1 protein, His-tagged - GBP1-53H from Creative Biomart
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GBP1 Peptide, Human - M34GP06142H from Creative Peptides
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GBP1 Blocking Peptide - CBP4417 from Cohesion Biosciences
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Human GBP1 Protein (His Tag) - 12569-H08H from ABclonal
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GBP1 Blocking Peptide - orb392762 from Biorbyt
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GBP1, Recombinant Protein - MBS2545485 from MyBioSource
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Guanylate Binding Protein 1, Interferon Inducible (GBP1), Recombinant Protein - MBS2086851 from MyBioSource
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