GBP1

Gene Symbol GBP1
Entrez Gene 2633
Alt Symbol -
Species Human
Gene Type protein-coding
Description guanylate binding protein 1, interferon-inducible
Other Description GBP-1|GTP-binding protein 1|guanine nucleotide-binding protein 1|guanylate binding protein 1, interferon-inducible, 67kDa|huGBP-1|interferon-induced guanylate-binding protein 1
Swissprots Q5T8M1 D3DT26 P32455
Accessions EAW73148 EAW73149 EAW73150 P32455 AB208912 BAD92149 AK291783 BAF84472 AK298032 BAG60334 AK303893 BAG64827 AY920436 AAX13805 BC002666 AAH02666 BF058809 BT006847 AAP35493 CB164272 CD676970 DQ890759 ABM81685 DQ893924 ABM84850 M55542 AAA35871 XM_006710573 XP_006710636 NM_002053 NP_002044
Function Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes. {ECO:0000269|PubMed:22106366}.
Subcellular Location Cytoplasm. Golgi apparatus membrane; Lipid- anchor; Cytoplasmic side. Secreted. Note=Secreted from endothelial cells in the cerebrospinal fluid, upon bacterial challenge and independently of interferon-gamma induction. Golgi membrane localization requires isoprenylation and the presence of another IFN-gamma-induced factor.

GBP1 CRISPR/Cas9 KO Plasmid (h) - sc-401778 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GBP1 HDR Plasmid (h) - sc-401778-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GBP1 Double Nickase Plasmid (h) - sc-401778-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GBP1 Double Nickase Plasmid (h2) - sc-401778-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GBP1 CRISPR Activation Plasmid (h) - sc-401778-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GBP1 CRISPR Activation Plasmid (h2) - sc-401778-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GBP1 Lentiviral Activation Particles (h) - sc-401778-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GBP1 Lentiviral Activation Particles (h2) - sc-401778-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GBP1 siRNA (h) - sc-72088 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GBP1 shRNA Plasmid (h) - sc-72088-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GBP1 shRNA (h) Lentiviral Particles - sc-72088-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GBP1 RNAi - H00002633-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN9168 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9168 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07762 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07762

GBP1 siRNA (Human) - CRH1748 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GBP1 - MBS8237811 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GBP1 CRISPR/Cas9 KO Plasmid (h2) - sc-401778-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GBP1 HDR Plasmid (h2) - sc-401778-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human GBP1(NM_002053.2) - SHH078923 from Creative biogene

Category siRNA
Species Reactivities Human

GBP1 shRNA Plasmid (Human) - CHH1748 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GBP1 miRNA 3'UTR clone - MiUTR1H-03972 from Creative biogene

Species Reactivities Human
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