NOXO1

Gene Symbol	NOXO1
Entrez Gene	124056
Alt Symbol	P41NOX, P41NOXA, P41NOXB, P41NOXC, SH3PXD5, SNX28
Species	Human
Gene Type	protein-coding
Description	NADPH oxidase organizer 1
Other Description	NADPH oxidase regulatory protein|Nox organizer 1|SH3 and PX domain-containing protein 5|nox-organizing protein 1|regulatory protein P41NOX
Swissprots	Q8NFA2 Q86YM1 Q8NFA3 Q96B73
Accessions	EAW85581 EAW85582 EAW85583 EAW85584 Q8NFA2 AB097667 BAC76711 AF532983 AAM97925 AF532984 AAM97926 AF532985 AAM97927 AF539796 AAN75141 AK292197 BAF84886 AK310198 AK313917 AY191359 AAO38665 AY255768 AAP13479 BC015917 AAH15917 DB009385 XM_005255099 XP_005255156 NM_001267721 NP_001254650 NM_144603 NP_653204 NM_172167 NP_751907 NM_172168 NP_751908
Function	Constitutively potentiates the superoxide-generating activity of NOX1 and NOX3 and is required for the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity. Isoform 3 is more potent than isoform 1 in activating NOX3. Together with NOXA1, may also substitute to NCF1/p47phox and NCF2/p67phox in supporting the phagocyte NOX2/gp91phox superoxide-generating activity. {ECO:0000269|PubMed:12657628, ECO:0000269|PubMed:14617635, ECO:0000269|PubMed:15326186, ECO:0000269|PubMed:15824103, ECO:0000269|PubMed:15949904, ECO:0000269|PubMed:16329988, ECO:0000269|PubMed:17126813, ECO:0000269|PubMed:19755710}.
Subcellular Location	Isoform 3: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Isoform 3 associates with the plasma membrane in a lipid-dependent manner.
Tissue Specificity	Expressed in testis, small and large intestines, liver, kidney and pancreas. Isoform 3 is mainly expressed in colon. Isoform 1 is preferentially expressed in testis. {ECO:0000269|PubMed:12657628, ECO:0000269|PubMed:15326186, ECO:0000269|PubMed:15949904}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

Human NOXO1 protein fragment - ab153593 from Abcam Category Protein Source Wheat germ Species Human

NOXO1 Antibody Blocking Peptide - LS-E5080 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NOXO1 Antibody Blocking Peptide - LS-E25690 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NOXO1 Antibody Blocking Peptide - LS-E23345 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human NOXO1 Protein - H00124056-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NOXO1-Antibody-Center-Blocking-Peptide - BP17494c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NOXO1 blocking peptide - GTX89749-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

NOXO1 Peptide - AC21-0521-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

NOXO1 - H00124056-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NOXO1 - H00124056-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NOXO1 Peptide - 45-979P from ProSci Category Peptide Species Human

Recombinant Human NADPH oxidase organizer 1(NOXO1) - CSB-YP015964HU CSB-EP015964HU CSB-BP015964HU CSB-MP015964HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NOXO1 (transcript variant b) - TP314973 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

NOXO1 (transcript variant c) - TP323385 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

NOXO1, Peptide - MBS426006 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

NOXO1 Recombinant Protein Antigen - NBP2-49663PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

NOXO1 Peptide, Human - M34GP10529H from Creative Peptides Category Peptide Source Synthetic. Species Human

NOXO1 Immunizing peptide - orb16822 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg

NADPH oxidase organizer 1 (NOXO1), Recombinant Protein - MBS1353745 from MyBioSource Category Protein Prices $1,145.00, $1,145.00, $1,375.00, $1,375.00, $1,825.00, $1,825.00, $2,290.00, $2,290.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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