NOXO1

Gene Symbol NOXO1
Entrez Gene 124056
Alt Symbol P41NOX, P41NOXA, P41NOXB, P41NOXC, SH3PXD5, SNX28
Species Human
Gene Type protein-coding
Description NADPH oxidase organizer 1
Other Description NADPH oxidase regulatory protein|Nox organizer 1|SH3 and PX domain-containing protein 5|nox-organizing protein 1|regulatory protein P41NOX
Swissprots Q8NFA2 Q86YM1 Q8NFA3 Q96B73
Accessions EAW85581 EAW85582 EAW85583 EAW85584 Q8NFA2 AB097667 BAC76711 AF532983 AAM97925 AF532984 AAM97926 AF532985 AAM97927 AF539796 AAN75141 AK292197 BAF84886 AK310198 AK313917 AY191359 AAO38665 AY255768 AAP13479 BC015917 AAH15917 DB009385 XM_005255099 XP_005255156 NM_001267721 NP_001254650 NM_144603 NP_653204 NM_172167 NP_751907 NM_172168 NP_751908
Function Constitutively potentiates the superoxide-generating activity of NOX1 and NOX3 and is required for the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity. Isoform 3 is more potent than isoform 1 in activating NOX3. Together with NOXA1, may also substitute to NCF1/p47phox and NCF2/p67phox in supporting the phagocyte NOX2/gp91phox superoxide-generating activity. {ECO:0000269|PubMed:12657628, ECO:0000269|PubMed:14617635, ECO:0000269|PubMed:15326186, ECO:0000269|PubMed:15824103, ECO:0000269|PubMed:15949904, ECO:0000269|PubMed:16329988, ECO:0000269|PubMed:17126813, ECO:0000269|PubMed:19755710}.
Subcellular Location Isoform 3: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Isoform 3 associates with the plasma membrane in a lipid-dependent manner.
Tissue Specificity Expressed in testis, small and large intestines, liver, kidney and pancreas. Isoform 3 is mainly expressed in colon. Isoform 1 is preferentially expressed in testis. {ECO:0000269|PubMed:12657628, ECO:0000269|PubMed:15326186, ECO:0000269|PubMed:15949904}.

NOXO1 (H-300) - sc-292093 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

NOXO1 (Q-12) - sc-79268 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NOXO1 (Q-12): sc-79268. Immunoperoxidase staining of formalin fixed, paraffin-embedded human small intestine tissue showing cytoplasmic staining of glandular cells.

Anti-NOXO1 antibody - ab97788 from Abcam

Prices $304.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-NOXO1 antibody (ab97788) at 1/1000 dilution + HCT116 whole cell lysate at 30 µg

Anti-NOXO1 antibody - ab173101 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-NOXO1 antibody (ab173101) at 1/100 dilution + HL60 cell lysate at 35 µg

Anti-NOXO1 antibody - ab34761 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NOXO1 antibody - ab77092 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Immunohistochemical analysis of paraffin embedded human kidney labelled with ab77092 at 10 µg/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Anti-NOXO1 antibody - ab130989 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-NOXO1 antibody (ab130989) at 1 µg/ml + Human fetal kidney lysate at 10 µgSecondaryGoat anti-Rabbit IgG HRP

Anti-NOXO1 Antibody (aa192-219, AP) - LS-C246632 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NOXO1 Antibody (aa192-219, APC) - LS-C246633 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NOXO1 Antibody (aa192-219, Biotin) - LS-C246634 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NOXO1 Antibody (aa192-219, FITC) - LS-C246636 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NOXO1 Antibody (aa192-219, PE) - LS-C246638 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NOXO1 Antibody (aa161-210) - LS-C151597 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
NOXO1 antibody Western Blot of Human Kidney.

Anti-NOXO1 Antibody (aa191-219) - LS-C323407 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NOXO1 Antibody (aa192-219, Azide-free, HRP) - LS-C248940 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NOXO1 Antibody (aa313-376) - LS-C185936 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate). A: HCT116 10% SDS PAGE. NOXO1 antibody diluted at 1:1000.

Anti-NOXO1 Antibody (aa192-219) - LS-C158415 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
NOXO1 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The NOXO1 antibody detected the NOXO1 protein (arrow).

Anti-NOXO1 Antibody (aa363-376) IHC-plus™ - LS-B3 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-NOXO1 antibody IHC of human renal tubular epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3 concentration 10 ug/ml.

Anti-NOXO1 Antibody (aa238-252) IHC-plus™ - LS-B485 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-NOXO1 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B485 concentration 10 ug/ml.

NOXO1 Antibody - NB300-950 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

NOXO1 Antibody - NBP1-77899 from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: NOXO1 Antibody [NBP1-77899] - NOXO1 antibody shows detection of a band ~50 kDa corresponding to human NOXO1 (arrowhead). Reactivity was observed in transfected human 293 cells and human HT-29 colon carcinoma cells (endogenous). Under these conditions endogenous NOXO1 detection was not observed in HeLa, HL-60, untransfected 293 or WT MEF cells. A 1:1,000 dilution of the primary antibody was used for detection followed by secondary antibody reactivity. Specific band reactivity was competed away when the antibody was pre-incubated with the peptide immunogen (data not shown).

NOXO1 Antibody - NBP1-33653 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

NOXO1 Antibody - H00124056-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Anti-NOXO1 antibody produced in rabbit - SAB2900367 from Sigma-Aldrich

Prices $464.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-NOXO1: <B>Cat. No.SAB2900367</B>: Colon: Formalin-Fixed Paraffin-Embedded (FFPE).

Anti-NOXO1 antibody produced in goat - SAB2500704 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
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