MAGED1

Gene Symbol	MAGED1
Entrez Gene	9500
Alt Symbol	DLXIN-1, NRAGE
Species	Human
Gene Type	protein-coding
Description	melanoma antigen family D1
Other Description	MAGE tumor antigen CCF|MAGE-D1 antigen|melanoma antigen family D, 1|melanoma-associated antigen D1|neurotrophin receptor-interacting MAGE homolog
Swissprots	Q8WY92 Q8IZ84 Q9H352 Q5VSH6 Q9HBT4 Q9UF36 Q9Y5V3
Accessions	EAW62896 EAW62897 Q9Y5V3 AF124440 AAD31421 AF132205 AAG35551 AF217963 AAG09704 AF258554 AAG23757 AF300328 AAQ14483 AK074092 BAB84918 AK298574 BAG60766 AK308706 AK314053 AL133628 CAB63752 BC014070 AAH14070 BC032473 AAH32473 BF529661 BG819042 BX422007 CD387872 XM_011530835 XP_011529137 NM_001005332 NP_001005332 NM_001005333 NP_001005333 NM_006986 NP_008917
Function	Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Plays a role in the circadian rythm regulation. May act as RORA co-regulator, modulating the expression of core clock genes such as ARNTL/BMAL1 and NFIL3, induced, or NR1D1, repressed. {ECO:0000269|PubMed:20864041}.
Subcellular Location	Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Nucleus {ECO:0000250}. Note=Expression shifts from the cytoplasm to the plasma membrane upon stimulation with NGF. {ECO:0000250}.
Tissue Specificity	Expressed in bone marrow stromal cells from both multiple myeloma patients and healthy donors. Seems to be ubiquitously expressed.
Top Pathways	Neurotrophin signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Melanoma-associated antigen D1 (MAGED1), Human, ELISA Kit - CSB-EL013351HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Melanoma-associated antigen D1 (MAGED1), Human, ELISA Kit - E01M0381 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

MAGED1 (Human) Matched Antibody Pair - H00009500-AP11 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

MAGED1 (Human) Matched Antibody Pair - H00009500-AP21 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

Melanoma-associated antigen D1 (MAGED1), ELISA Kit - MBS7209990 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-associated antigen D1 (MAGED1), ELISA Kit - MBS7228701 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-associated antigen D1 (MAGED1), ELISA Kit - MBS7232571 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-associated antigen D1 (MAGED1), ELISA Kit - MBS7224901 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-associated antigen D1 (MAGED1), ELISA Kit - MBS7226784 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-associated antigen D1 (MAGED1), ELISA Kit - MBS7221923 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-associated antigen D1 (MAGED1), ELISA Kit - MBS7243231 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-associated antigen D1 (MAGED1), ELISA Kit - MBS7251935 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-associated antigen D1 (MAGED1), ELISA Kit - MBS7222509 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Melanoma-associated antigen D1 (MAGED1), ELISA Kit - MBS7227896 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

melanoma antigen family D, 1, ELISA Kit - MBS910769 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human MAGED1 is typically less than 7.81 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 31.25 pg/ml -2000 pg/ml.

Melanoma associated antigen D1 (MAGED1), ELISA Kit - MBS7210460 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human Melanoma-associated antigen D1(MAGED1) ELISA kit - CSB-EL013351HU from Cusabio Category ELISA Kit Sensitivity 7.81 pg/ml. Range 31.25 pg/ml-2000 pg/ml

Human Melanoma-associated antigen D1 (MAGED1) ELISA Kit - EKC34579 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 7.81 pg/ml Range 31.25 pg/ml-2000 pg/ml

Human MAGED1 ELISA Kit - E024026 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of human MAGED1 is typically less than 7.81 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the m

anti-MAGED1 antibody - ARG55821 from Arigo Biolaboratories Category ELISA Kit

MAGED1 ELISA Kit (Human) (OKCA01354) - OKCA01354 from Aviva Systems Biology Category ELISA Kit Prices $600.00 Sizes 96 wells Sensitivity 7.81 pg/mL Range 31.25 - 2,000 pg/mL

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