Gene Symbol | DUSP26 |
---|---|
Entrez Gene | 78986 |
Alt Symbol | DSP-4, DUSP24, LDP-4, MKP-8, MKP8, NATA1, NEAP, SKRP3 |
Species | Human |
Gene Type | protein-coding |
Description | dual specificity phosphatase 26 (putative) |
Other Description | MAP kinase phosphatase 8|Novel amplified gene in thyroid anaplastic cancer|dual specificity phosphatase SKRP3|dual specificity protein phosphatase 26|low-molecular-mass dual-specificity phosphatase 4|mitogen-activated protein kinase phosphatase 8|neuroendocrine-associated phosphatase |
Swissprots | D3DSV8 Q9BV47 Q9BTW0 |
Accessions | EAW63392 EAW63393 EAW63394 Q9BV47 AB103376 BAD91015 AB158288 BAD82942 AB237597 BAE46506 AK055704 BAB70991 AY902194 AAX07132 BC001613 AAH01613 BC003115 AAH03115 BC067804 AAH67804 BI753746 BI834891 BP196801 DA132743 HQ447174 ADQ31661 XM_005273633 XP_005273690 NM_001305115 NP_001292044 NM_001305116 NP_001292045 NM_024025 NP_076930 |
Function | Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK). {ECO:0000269|PubMed:15796912, ECO:0000269|PubMed:16581800, ECO:0000269|PubMed:16924234, ECO:0000269|PubMed:17001450}. |
Subcellular Location | Cytoplasm. Nucleus. Golgi apparatus. |
Tissue Specificity | Brain. In the brain it is expressed ubiquitously except in the hippocampus. Expressed in embryonal cancers (retinoblastoma, neuroepithilioma and neuroblastoma) and in anaplatic thyroid cancer. {ECO:0000269|PubMed:15796912, ECO:0000269|PubMed:16581800, ECO:0000269|PubMed:16924234, ECO:0000269|PubMed:17001450}. |
DUSP26 (C-15) - sc-79458 from Santa Cruz Biotechnology
|
||||||||
Anti-DUSP26 antibody - ab128582 from Abcam
|
||||||||
Anti-DUSP26 antibody - ab172670 from Abcam
|
||||||||
Anti-DUSP26 antibody - ab115571 from Abcam
|
||||||||
Anti-DUSP26 antibody - ab56136 from Abcam
|
||||||||
Anti-DUSP26 / MKP8 Antibody (aa2-211) - LS-C178985 from LifeSpan Bioscience
|
||||||||
Anti-DUSP26 / MKP8 Antibody (Internal) IHC-plus⢠- LS-A6784 from LifeSpan Bioscience
|
||||||||
Anti-DUSP26 / MKP8 Antibody (Internal) IHC-plus⢠- LS-A6787 from LifeSpan Bioscience
|
||||||||
Anti-DUSP26 / MKP8 Antibody (aa22-117) - LS-C186059 from LifeSpan Bioscience
|
||||||||
Anti-DUSP26 / MKP8 Antibody (Internal) IHC-plus⢠- LS-A6785 from LifeSpan Bioscience
|
||||||||
Anti-DUSP26 / MKP8 Antibody (C-Terminus) IHC-plus⢠- LS-A6788 from LifeSpan Bioscience
|
||||||||
DUSP26 Antibody - NBP1-31254 from Novus Biologicals
|
||||||||
DUSP26 Antibody - NBP2-33880 from Novus Biologicals
|
||||||||
DUSP26 Antibody - H00078986-B01 from Novus Biologicals
|
||||||||
DUSP26 Antibody - H00078986-A01 from Novus Biologicals
|
||||||||
Anti-DUSP26 antibody produced in rabbit - SAB2701039 from Sigma-Aldrich
|
||||||||
Anti-DUSP26 antibody produced in rabbit - HPA018221 from Sigma-Aldrich
|
||||||||
Anti-DUSP26 (AB2) antibody produced in rabbit - SAB2900160 from Sigma-Aldrich
|
||||||||
Anti-DUSP26 (AB1) antibody produced in rabbit - SAB2900159 from Sigma-Aldrich
|
||||||||
DUSP26 antibody - 70R-35973 from Fitzgerald
|
||||||||
Anti -DUSP26 (Dual Specificity Protein Phosphatase 26, DSP-4, Dual Specificity PhosphataseSKRP3, Low-molecular-mass Dual-specificity Phosphatase 4, LDP4, LDP-4, Mitogen-activatedProtein Kinase Phosphatase 8, MAP Kinase Phosphatase 8, MKP8, MKP-8, Novel Amplif - D9840-69 from USBiological Life Science
|
||||||||
Anti -DUSP26 (Dual Specificity Protein Phosphatase 26, DSP-4, Dual Specificity PhosphataseSKRP3, Low-molecular-mass Dual-specificity Phosphatase 4, LDP4, LDP-4, Mitogen-activatedProtein Kinase Phosphatase 8, MAP Kinase Phosphatase 8, MKP8, MKP-8, Novel Amplif - D9840-69B from USBiological Life Science
|
||||||||
DUSP26 antibody (OAGA00754) - OAGA00754 from Aviva Systems Biology
|
||||||||
DUSP26 Antibody (OALA01079) - OALA01079 from Aviva Systems Biology
|
||||||||
DUSP26 Antibody (OALA01080) - OALA01080 from Aviva Systems Biology
|