DUSP26

Gene Symbol DUSP26
Entrez Gene 78986
Alt Symbol DSP-4, DUSP24, LDP-4, MKP-8, MKP8, NATA1, NEAP, SKRP3
Species Human
Gene Type protein-coding
Description dual specificity phosphatase 26 (putative)
Other Description MAP kinase phosphatase 8|Novel amplified gene in thyroid anaplastic cancer|dual specificity phosphatase SKRP3|dual specificity protein phosphatase 26|low-molecular-mass dual-specificity phosphatase 4|mitogen-activated protein kinase phosphatase 8|neuroendocrine-associated phosphatase
Swissprots D3DSV8 Q9BV47 Q9BTW0
Accessions EAW63392 EAW63393 EAW63394 Q9BV47 AB103376 BAD91015 AB158288 BAD82942 AB237597 BAE46506 AK055704 BAB70991 AY902194 AAX07132 BC001613 AAH01613 BC003115 AAH03115 BC067804 AAH67804 BI753746 BI834891 BP196801 DA132743 HQ447174 ADQ31661 XM_005273633 XP_005273690 NM_001305115 NP_001292044 NM_001305116 NP_001292045 NM_024025 NP_076930
Function Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK). {ECO:0000269|PubMed:15796912, ECO:0000269|PubMed:16581800, ECO:0000269|PubMed:16924234, ECO:0000269|PubMed:17001450}.
Subcellular Location Cytoplasm. Nucleus. Golgi apparatus.
Tissue Specificity Brain. In the brain it is expressed ubiquitously except in the hippocampus. Expressed in embryonal cancers (retinoblastoma, neuroepithilioma and neuroblastoma) and in anaplatic thyroid cancer. {ECO:0000269|PubMed:15796912, ECO:0000269|PubMed:16581800, ECO:0000269|PubMed:16924234, ECO:0000269|PubMed:17001450}.

DUSP26-Over-expression-Lysate - LY10157a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag DUSP26 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the DUSP26 gene (Lane 2, Cat. #LY10157a).

DUSP26 293T Cell Transient Overexpression Lysate(Denatured) - H00078986-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

DUSP26 293 Cell Lysate - 405728 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

DUSP26 Overexpression Lysate (Native) - NBL1-10052 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: DUSP26 Overexpression Lysate (Adult Normal) [NBL1-10052] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for DUSP26.

DUSP26 Over-expression Lysate Product - GWB-50A6D0 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

DUSP26 Overexpression Lysate (Denatured) - H00078986-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Panoply™ Human DUSP26 Knockdown Stable Cell Line - CSC-DC004612 from Creative biogene

Category Cell Line
Species Human
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