DUSP26

Gene Symbol DUSP26
Entrez Gene 78986
Alt Symbol DSP-4, DUSP24, LDP-4, MKP-8, MKP8, NATA1, NEAP, SKRP3
Species Human
Gene Type protein-coding
Description dual specificity phosphatase 26 (putative)
Other Description MAP kinase phosphatase 8|Novel amplified gene in thyroid anaplastic cancer|dual specificity phosphatase SKRP3|dual specificity protein phosphatase 26|low-molecular-mass dual-specificity phosphatase 4|mitogen-activated protein kinase phosphatase 8|neuroendocrine-associated phosphatase
Swissprots D3DSV8 Q9BV47 Q9BTW0
Accessions EAW63392 EAW63393 EAW63394 Q9BV47 AB103376 BAD91015 AB158288 BAD82942 AB237597 BAE46506 AK055704 BAB70991 AY902194 AAX07132 BC001613 AAH01613 BC003115 AAH03115 BC067804 AAH67804 BI753746 BI834891 BP196801 DA132743 HQ447174 ADQ31661 XM_005273633 XP_005273690 NM_001305115 NP_001292044 NM_001305116 NP_001292045 NM_024025 NP_076930
Function Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK). {ECO:0000269|PubMed:15796912, ECO:0000269|PubMed:16581800, ECO:0000269|PubMed:16924234, ECO:0000269|PubMed:17001450}.
Subcellular Location Cytoplasm. Nucleus. Golgi apparatus.
Tissue Specificity Brain. In the brain it is expressed ubiquitously except in the hippocampus. Expressed in embryonal cancers (retinoblastoma, neuroepithilioma and neuroblastoma) and in anaplatic thyroid cancer. {ECO:0000269|PubMed:15796912, ECO:0000269|PubMed:16581800, ECO:0000269|PubMed:16924234, ECO:0000269|PubMed:17001450}.

DUSP26 CRISPR/Cas9 KO Plasmid (h) - sc-406454 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DUSP26 HDR Plasmid (h) - sc-406454-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DUSP26 Double Nickase Plasmid (h) - sc-406454-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DUSP26 Double Nickase Plasmid (h2) - sc-406454-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DUSP26 CRISPR Activation Plasmid (h) - sc-406454-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DUSP26 CRISPR Activation Plasmid (h2) - sc-406454-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DUSP26 Lentiviral Activation Particles (h) - sc-406454-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DUSP26 Lentiviral Activation Particles (h2) - sc-406454-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DUSP26 siRNA (h) - sc-77204 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DUSP26 shRNA Plasmid (h) - sc-77204-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DUSP26 shRNA (h) Lentiviral Particles - sc-77204-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU020931 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® Human Phosphatase - SIHP0132 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0131 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0130 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN7554 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7554 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12276 from Sigma-Aldrich

Category miRNA

DUSP26 siRNA (Human) - CRJ2232 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DUSP26 RNAi - H00078986-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

DUSP26 - MBS827155 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DUSP26 (NM_024025.1) - SHH281829 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human DUSP26(NM_024025.1) - SHH019163 from Creative biogene

Category siRNA
Species Reactivities Human

DUSP26 shRNA Plasmid (Human) - CHJ2232 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DUSP26 miRNA 3'UTR clone - MiUTR1H-03037 from Creative biogene

Species Reactivities Human
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