Gene Symbol | AEBP1 |
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Entrez Gene | 165 |
Alt Symbol | ACLP |
Species | Human |
Gene Type | protein-coding |
Description | AE binding protein 1 |
Other Description | adipocyte enhancer-binding protein 1|aortic carboxypeptidase-like protein |
Swissprots | Q59ER7 Q14113 Q7KZ79 Q6ZSC7 Q8IUX7 |
Accessions | EAL23768 EAW61119 Q8IUX7 AB209744 BAD92981 AF053944 AAC25585 AK090931 BAG52248 AK127541 BAC87026 AK296001 BAG58775 BC038588 AAH38588 BM672693 D86479 BAA13094 DB213495 XM_011515162 XP_011513464 NM_001129 NP_001120 |
Function | May positively regulate MAP-kinase activity in adipocytes, leading to enhanced adipocyte proliferation and reduced adipocyte differentiation. May also positively regulate NF-kappa-B activity in macrophages by promoting the phosphorylation and subsequent degradation of I-kappa-B-alpha (NFKBIA), leading to enhanced macrophage inflammatory responsiveness. Can act as a transcriptional repressor. {ECO:0000250}. |
Subcellular Location | Isoform 1: Secreted {ECO:0000250}. |
Tissue Specificity | Expressed in osteoblast and visceral fat. {ECO:0000269|PubMed:8920928}. |
ACLP (N-14) - sc-23051 from Santa Cruz Biotechnology
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ACLP (N-14) - sc-21449 from Santa Cruz Biotechnology
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ACLP/AEBP1 (C-15) - sc-21451 from Santa Cruz Biotechnology
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ACLP/AEBP1 (E-13) - sc-21453 from Santa Cruz Biotechnology
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ACLP/AEBP1 (G-1) - sc-271374 from Santa Cruz Biotechnology
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ACLP/AEBP1 (H-164) - sc-32919 from Santa Cruz Biotechnology
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Anti-AE binding protein 1 antibody - ab54820 from Abcam
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Anti-AE binding protein 1 antibody [EPR7733(2)] - ab168355 from Abcam
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Anti-ACLP / AEBP1 Antibody (aa334-364, APC) - LS-C250983 from LifeSpan Bioscience
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Anti-ACLP / AEBP1 Antibody (aa334-364, AP) - LS-C250982 from LifeSpan Bioscience
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Anti-ACLP / AEBP1 Antibody (aa334-364, Biotin) - LS-C250984 from LifeSpan Bioscience
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Anti-ACLP / AEBP1 Antibody (aa334-364, Azide-free, HRP) - LS-C250986 from LifeSpan Bioscience
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Anti-ACLP / AEBP1 Antibody (aa334-364, PE) - LS-C250987 from LifeSpan Bioscience
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Anti-ACLP / AEBP1 Antibody (aa334-364, FITC) - LS-C250985 from LifeSpan Bioscience
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Anti-ACLP / AEBP1 Antibody (aa85-134) - LS-C29694 from LifeSpan Bioscience
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Anti-ACLP / AEBP1 Antibody (clone 1D2) - LS-C133036 from LifeSpan Bioscience
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Anti-ACLP / AEBP1 Antibody (aa334-364) - LS-C156122 from LifeSpan Bioscience
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Anti-ACLP / AEBP1 Antibody (aa341-372) - LS-C319357 from LifeSpan Bioscience
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AE Binding Protein 1/ACLP Antibody (590831) - MAB6425 from Novus Biologicals
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AE Binding Protein 1/ACLP Antibody (1D2) - H00000165-M01 from Novus Biologicals
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AE Binding Protein 1/ACLP Antibody - H00000165-A01 from Novus Biologicals
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Rabbit Anti-AEBP1 Polyclonal Antibody - bs-0322R from Bioss
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Anti-AEBP1 antibody produced in rabbit - AV31592 from Sigma-Aldrich
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Monoclonal Anti-AEBP1 antibody produced in mouse - WH0000165M1 from Sigma-Aldrich
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AEBP1 antibody - N-terminal region (ARP31592_P050) - ARP31592_P050 from Aviva Systems Biology
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