CHM

Gene Symbol	CHM
Entrez Gene	1121
Alt Symbol	DXS540, GGTA, HSD-32, REP-1, TCD
Species	Human
Gene Type	protein-coding
Description	choroideremia (Rab escort protein 1)
Other Description	rab proteins geranylgeranyltransferase component A 1
Swissprots	O43732 A1L4D2 P24386
Accessions	AAD13814 CAV30743 EAW98559 P24386 AK095883 BAC04640 AK291160 BAF83849 AK299323 BAG61331 AK312443 AY255796 AAP15253 BC032237 BC063522 BC065702 AAH65702 BC073987 AAH73987 BC105969 AAI05970 BC130494 AAI30495 BC130496 AAI30497 BC156457 AAI56458 BC172532 AAI72532 M83773 AAA61032 S60753 AAD14934 X57637 CAA40855 X78121 CAA55011 XM_006724615 XP_006724678 XM_011530839 XP_011529141 NM_000390 NP_000381 NM_001145414 NP_001138886 NM_001037312
Function	Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation. {ECO:0000269|PubMed:18532927, ECO:0000269|PubMed:7957092}.
Subcellular Location	Cytoplasm, cytosol {ECO:0000269|PubMed:7957092}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active rat CHM full length protein - ab91070 from Abcam Category Protein Prices $192.00 Sizes 50 µg Source Spodoptera frugiperda Species Rat

CHM / REP1 Antibody Blocking Peptide - LS-E10680 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CHM Blocking Peptide - 33R-5032 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Recombinant Human Rab proteins geranylgeranyltransferase component A 1(CHM) - CSB-YP005356HU CSB-EP005356HU CSB-BP005356HU CSB-MP005356HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CHM Protein - abx163200 from Abbexa Category Protein Species Human

Recombinant Homo sapiens (Human) Rab proteins geranylgeranyltransferase component A 1 - CSB-EP005356HU from Cusabio Category Protein Source E.coli Species Human

CHM Recombinant Protein Antigen - NBP1-84954PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CHM-Blocking-Peptide-Center - BP20084c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CHM Peptide, Human - M34GP03098H from Creative Peptides Category Peptide Source Synthetic. Species Human

CHM Recombinant Protein (OPCA03417) - OPCA03417 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

Human CHM protein - orb358673 from Biorbyt Category Protein Prices $221.00, $366.00, $646.00, $1,071.00, $1,692.00 Sizes 10 μg, 50 μg, 200 μg, 500 μg, 1 mg Species Human

Recombinant Human Rab proteins geranylgeranyltransferase component A 1(CHM) - AP73915 from Signalway Antibody Category Protein Prices $105.00, $260.00, $454.00, $735.00, $1,240.00, $1,980.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

Rab proteins geranylgeranyltransferase component A 1, Recombinant Protein - MBS9423495 from MyBioSource Category Protein Prices $165.00, $280.00, $435.00, $665.00, $1,080.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg Source E Coli Species Human

Rab proteins geranylgeranyltransferase component A 1, Recombinant Protein - MBS958917 from MyBioSource Category Protein Prices $110.00, $285.00, $460.00, $490.00, $750.00, $1,125.00, $1,180.00, $1,245.00, $1,500.00, $1,525.00, $1,580.00, $1,725.00, $2,255.00, $2,260.00, $2,610.00, $2,965.00 Sizes 10 µg (E-Coli), 100 µg (E-Coli), 200 µg (E-Coli), 50 µg (E-Coli), 500 µg (E-Coli), 50 µg (Yeast), 1 mg (E-Coli), 50 µg (Baculovirus), 50 µg (Mammalian-Cell), 200 µg (Yeast), 100 µg (Baculovirus), 500 µg (Yeast), 100 µg (Mammalian-Cell), 500 µg (Baculovirus), 1 mg (Yeast), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Human Rab proteins geranylgeranyltransferase component A 1 (CHM) - RPC21093 from Biomatik Category Protein Prices $187.00, $342.00, $1,692.00 Sizes 50 µg, 100 µg, 1 mg Source E.coli Species Human

CHM fusion protein - Ag23166 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

Recombinant Human CHM Protein (1-653 aa), His-tagged - CHM-1919H from Creative Biomart Category Protein Source E. coli Species Human

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