TFAP2A

Gene Symbol TFAP2A
Entrez Gene 7020
Alt Symbol AP-2, AP-2alpha, AP2TF, BOFS, TFAP2
Species Human
Gene Type protein-coding
Description transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
Other Description AP-2 transcription factor|AP2-alpha|activating enhancer-binding protein 2-alpha|activator protein 2|transcription factor AP-2-alpha
Swissprots Q13777 P05549 Q5TAV5 Q8N1C6
Accessions AAK54356 CAA64522 CAB59735 EAW55248 EAW55249 EAW55250 EAW55251 P05549 AK296737 BAH12422 BC017754 AAH17754 BC071713 CB990517 DQ891099 ABM82025 DQ894281 ABM85207 FJ794945 ACN93799 M36711 AAA35539 M61156 AAA02487 X52611 CAA36842 XM_006715175 XP_006715238 XM_011514833 XP_011513135 NM_001032280 NP_001027451 NM_001042425 NP_001035890 NM_003220 NP_003211
Function Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region. {ECO:0000269|PubMed:11694877, ECO:0000269|PubMed:12586840}.
Subcellular Location Nucleus {ECO:0000269|PubMed:12586840}.

AP-2α (C83E10) Rabbit mAb - 3215 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone C83E10
Western blot analysis of extracts from various cell types using AP-2α (C83E10) Rabbit mAb.

AP-2α Antibody - 3208 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines, using AP-2α Antibody.

AP-2α (3B5) - sc-12726 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AP-2α (3B5): sc-12726. Immunoperoxidase staining of formalin fixed, paraffin-embedded human malignant melanoma showing nuclear staining of tumor cells. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

AP-2α (C-18) - sc-184 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
AP-2α (C-18): sc-184. Western blot analysis of AP-2α expression in phorbol ester-induced HeLa nuclear extract.

AP-2α (8G8/5) - sc-53164 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AP-2α (8G8/5): sc-53164. Western blot analysis of AP-2α expression in HeLa nuclear extract.

AP-2α (B-11) - sc-55485 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AP-2α (B-11): sc-55485. Immunoperoxidase staining of formalin fixed, paraffin-embedded human placenta tissue showing nuclear staining of decidual cells.

AP-2α (C-17) - sc-6312 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AP-2α (C-17): sc-6312. Immunofluorescence staining of paraformaldehyde-fixed HeLa cells showing nuclear localization. Kindly provided byLene Melsaether Grvdal, Oslo University, Norway.

AP-2α (D-12) - sc-25343 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AP-2α (D-12): sc-25343. Western blot analysis of Ap-2α expression in HeLa whole cell lysate.

AP-2α (H-79) - sc-8975 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
AP-2α (H-79): sc-8975. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear staining.

AP-2α/β (3H547) - sc-70361 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AP-2α/β (3H547): sc-70361. Western blot analysis of AP-2α expression in non-transfected: sc-117752 (A) and mouse AP-2α transfected: sc-118446 (B) 293T whole cell lysates.

AP-2α/β (A6/2/2) - sc-53163 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AP-2α/β (A6/2/2): sc-53163. Western blot analysis of AP-2α expression in non-transfected: sc-117752 (A) and mouse AP-2α transfected: sc-118446 (B) 293T whole cell lysates.

Anti-AP2 alpha + beta antibody - ab11907 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-AP2 alpha + beta antibody [A6/2/2] - ab61 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone A6/2/2
ICC/IF image of ab61 stained HeLa cells. The cells were 4% PFA fixed (10 min) and then incubated in 1%BSA / 10% normal Goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab61, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 Goat anti-Mouse IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-AP2 alpha + beta antibody - C-terminal - ab166783 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human placenta tissue labeling AP2 alpha + beta with ab166783 at 5 µg/ml.

Anti-AP2 alpha antibody [A6/2/2] - ab110114 from Abcam

Prices $378.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone A6/2/2
ab110114 at 20 µg/ml staining TFAP2A in formalin-fixed, paraffin-embedded Human Breast tissue, followed by a biotinylated anti-mouse IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-AP2 alpha antibody [AP2a 8G8/5] - ab18112 from Abcam

Prices $378.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone AP2a 8G8/5
Immunohistochemical analysis of bladder cancer tissue, staining AP2 alpha with ab18112 at 1/40 dilution.

Anti-AP2 alpha antibody [EPR2688(2)] - ab108311 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR2688(2)
All lanes : Anti-AP2 alpha antibody [EPR2688(2)] (ab108311) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : JAR cell lysateLane 3 : RAW264.7 cell lysateLysates/proteins at 10 µg per lane.

Anti-AP2 alpha antibody - N-terminal - ab176436 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-AP2 alpha antibody - N-terminal (ab176436) at 1/1000 dilutionLane 1 : Jurkat cell extractsLane 2 : HeLa cell extracts

Anti-TFAP2A / AP-2 Antibody (Lys431) - LS-C175920 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of AP-2/ (K431) pAb in paraffin-embedded human lung carcinoma tissue.

Anti-TFAP2A / AP-2 Antibody (aa166-223) - LS-C20683 from LifeSpan Bioscience

Prices $455.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal

Anti-TFAP2A / AP-2 Antibody - LS-C20684 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-TFAP2A / AP-2 Antibody (C-Terminus) - LS-C34989 from LifeSpan Bioscience

Prices $530.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-TFAP2A / AP-2 Antibody - LS-C34990 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TFAP2A / AP-2 Antibody (aa214-672) - LS-C69071 from LifeSpan Bioscience

Prices $530.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TFAP2A / AP-2 Antibody - LS-C76480 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
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