TFAP2A

Gene Symbol	TFAP2A
Entrez Gene	7020
Alt Symbol	AP-2, AP-2alpha, AP2TF, BOFS, TFAP2
Species	Human
Gene Type	protein-coding
Description	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
Other Description	AP-2 transcription factor|AP2-alpha|activating enhancer-binding protein 2-alpha|activator protein 2|transcription factor AP-2-alpha
Swissprots	Q13777 P05549 Q5TAV5 Q8N1C6
Accessions	AAK54356 CAA64522 CAB59735 EAW55248 EAW55249 EAW55250 EAW55251 P05549 AK296737 BAH12422 BC017754 AAH17754 BC071713 CB990517 DQ891099 ABM82025 DQ894281 ABM85207 FJ794945 ACN93799 M36711 AAA35539 M61156 AAA02487 X52611 CAA36842 XM_006715175 XP_006715238 XM_011514833 XP_011513135 NM_001032280 NP_001027451 NM_001042425 NP_001035890 NM_003220 NP_003211
Function	Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region. {ECO:0000269|PubMed:11694877, ECO:0000269|PubMed:12586840}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:12586840}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

AP-2α CRISPR/Cas9 KO Plasmid (h) - sc-400935 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

AP-2α HDR Plasmid (h) - sc-400935-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

AP-2α Double Nickase Plasmid (h) - sc-400935-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

AP-2α Double Nickase Plasmid (h2) - sc-400935-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

AP-2α CRISPR Activation Plasmid (h) - sc-400935-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

AP-2α CRISPR Activation Plasmid (h2) - sc-400935-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

AP-2α Lentiviral Activation Particles (h) - sc-400935-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

AP-2α Lentiviral Activation Particles (h2) - sc-400935-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

AP-2α siRNA (h) - sc-105074 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

AP-2α shRNA Plasmid (h) - sc-105074-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

AP-2α shRNA (h) Lentiviral Particles - sc-105074-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

AP2 alpha RNAi - H00007020-R01V from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

AP2 alpha RNAi - H00007020-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

AP2 alpha RNAi - H00007020-R01 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU070021 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21244 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21244 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10259 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr10259

TFAP2A siRNA (Human) - CRH4795 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

TFAP2A - MBS8236767 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human TFAP2A(NM_001032280.2) - SHL066430 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human TFAP2A(NM_003220.2) - SHL066446 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human TFAP2A(NM_001032280.2) - SHL066564 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human TFAP2A(NM_003220.2) - SHL066566 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human TFAP2A(NM_001042425.1) - SHL066594 from Creative biogene Category siRNA Species Reactivities Human

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