SIT1

Gene Symbol	SIT1
Entrez Gene	27240
Alt Symbol	SIT, SIT-R
Species	Human
Gene Type	protein-coding
Description	signaling threshold regulating transmembrane adaptor 1
Other Description	SHP-2 interacting transmembrane adaptor protein|SHP2 interacting transmembrane adaptor|SHP2-interacting transmembrane adapter protein|SHP2-interacting transmembrane adaptor protein|gp30/40|signaling threshold-regulating transmembrane adapter 1|suppression inducing transmembrane adaptor 1|suppression-inducing transmembrane adapter 1
Swissprots	Q9Y3P8 B2RBP9
Accessions	CAC81313 EAW58370 Q9Y3P8 AA310964 AA746595 AJ010059 CAB41504 AK314758 BAG37296 BC102029 AAI02030 BC104491 AAI04492 BC107484 AAI07485 BM919490 JQ924063 AFK32776 NM_014450 NP_055265
Function	Negatively regulates TCR (T-cell antigen receptor)- mediated signaling in T-cells. Involved in positive selection of T-cells. {ECO:0000269|PubMed:10209036}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:10209036}; Single-pass type I membrane protein {ECO:0000269|PubMed:10209036}.
Tissue Specificity	Specifically expressed in T- and B-cells. Present in plasma cells but not in germinal center B-cells (at protein level). Expressed in T- and B-cell lymphoma. {ECO:0000269|PubMed:10209036, ECO:0000269|PubMed:16160011}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Signaling Lymphocytic Activation Molecule Family, Member 7, ELISA Kit - MBS077309 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Signaling Lymphocytic Activation Molecule Family, Member 7 (SLAMF7), ELISA Kit - MBS2020423 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of SLAMF7 is typically less than 0.055ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.156-10ng/mL

signaling threshold regulating transmembrane adaptor 1, ELISA Kit - MBS9337082 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

anti-SIT antibody [SIT-01] - ARG63095 from Arigo Biolaboratories Category ELISA Kit

anti-SIT antibody [SIT-01] (PE) - ARG53961 from Arigo Biolaboratories Category ELISA Kit

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