SIT1

Gene Symbol	SIT1
Entrez Gene	27240
Alt Symbol	SIT, SIT-R
Species	Human
Gene Type	protein-coding
Description	signaling threshold regulating transmembrane adaptor 1
Other Description	SHP-2 interacting transmembrane adaptor protein|SHP2 interacting transmembrane adaptor|SHP2-interacting transmembrane adapter protein|SHP2-interacting transmembrane adaptor protein|gp30/40|signaling threshold-regulating transmembrane adapter 1|suppression inducing transmembrane adaptor 1|suppression-inducing transmembrane adapter 1
Swissprots	Q9Y3P8 B2RBP9
Accessions	CAC81313 EAW58370 Q9Y3P8 AA310964 AA746595 AJ010059 CAB41504 AK314758 BAG37296 BC102029 AAI02030 BC104491 AAI04492 BC107484 AAI07485 BM919490 JQ924063 AFK32776 NM_014450 NP_055265
Function	Negatively regulates TCR (T-cell antigen receptor)- mediated signaling in T-cells. Involved in positive selection of T-cells. {ECO:0000269|PubMed:10209036}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:10209036}; Single-pass type I membrane protein {ECO:0000269|PubMed:10209036}.
Tissue Specificity	Specifically expressed in T- and B-cells. Present in plasma cells but not in germinal center B-cells (at protein level). Expressed in T- and B-cell lymphoma. {ECO:0000269|PubMed:10209036, ECO:0000269|PubMed:16160011}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SIT protein fragment - ab113580 from Abcam Category Protein Source E. coli Species Human

Human SIT protein fragment - ab151377 from Abcam Category Protein Source E. coli Species Human

SIT1-Antibody-C-term-Blocking-Peptide - BP16787b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SIT1 blocking peptide - GTX88197-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

SIT Peptide - AC21-2129-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

SIT1 / SIT (62-196, HIS-Tag) - AR39151PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 50 µg Source E. coli Species Human

SIT1 / SIT (62-196, HIS-Tag) - AR39151PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 10 µg Source E. coli Species Human

SIT1 / SIT - P4317 from Acris Antibodies Category Protein Prices $500.00 Sizes 10 µg Species Human

Signaling Threshold Regulating Transmembrane Adaptor 1, Human Recombinant - 228-13367-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Human Signaling Threshold Regulating Transmembrane Adaptor 1 - 228-13367-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human Signaling Threshold Regulating Transmembrane Adaptor 1 - 228-13367-3 from RayBiotech Category Protein Prices $1,448.00 Sizes 3 µg Source Escherichia Coli. Species Human

Signaling Threshold-Regulating Transmembrane Adapter 1, SIT1, Human, Recombinant - 19-C292 from ARP American Research Products Category Protein Prices $169.00 Sizes 10 µg Source E. coli Species Human

SIT1, 1-196aa, Human, His tag, E.coli - 01-P1209 from ARP American Research Products Category Protein Prices $159.00, $369.00, $849.00 Sizes 2 µg, 10 µg, 50 µg Species Human

SIT1 Peptide - 42-535P from ProSci Category Peptide

SIT1 fusion protein - Ag15875 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

SIT1 Human - PRPS-935 from NeoScientific Category Protein Prices $65.00, $169.00, $1,560.00 Sizes 1 µg, 5 µg, 50 µg Source Escherichia Coli. Species Human

Recombinant Human SIT1 Protein - BP001755-C292 from Syd Labs Category Protein Prices $180.00, $528.00, $2,640.00 Sizes 10 µg, 50 µg, 1 mg Source E. coli-derived. Species Human

Recombinant Human SIT1 Protein - BP001755-PRO-928 from Syd Labs Category Protein Prices $160.00, $1,200.00 Sizes 5 µg, 50 µg Source E. coli-?derived. Species Human

SIT1, 1-196aa, Recombinant Protein - GWB-P0829J from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 10 μg, 50 μg Source E.coli Species Human

Recombinant Human SIT1, His-tagged - SIT1-30868TH from Creative Biomart Category Protein Source E. coli

Recombinant Human Signaling Threshold Regulating Transmembrane Adaptor 1, His-tagged - SIT1-6861H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human SIT1, His-tagged - SIT1-2685H from Creative Biomart Category Protein Source E.coli Species Human

SIT1 1-196aa - CMB-1042 from Reagent Proteins Category Protein Prices $469.00, $889.00 Sizes 10.00 µg, 50.00 µg Source E.coli Species Human

Recombinant Signaling Threshold Regulating Transmembrane Adaptor 1 (SIT1) - RPH166Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

SIT1, 1-196aa, Human, His tag, E.coli - ATGP1209 from ATGen Category Protein Prices $240.00, $720.00 Sizes 10 µg, 50 µg Species Human

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