SIT1

Gene Symbol SIT1
Entrez Gene 27240
Alt Symbol SIT, SIT-R
Species Human
Gene Type protein-coding
Description signaling threshold regulating transmembrane adaptor 1
Other Description SHP-2 interacting transmembrane adaptor protein|SHP2 interacting transmembrane adaptor|SHP2-interacting transmembrane adapter protein|SHP2-interacting transmembrane adaptor protein|gp30/40|signaling threshold-regulating transmembrane adapter 1|suppression inducing transmembrane adaptor 1|suppression-inducing transmembrane adapter 1
Swissprots Q9Y3P8 B2RBP9
Accessions CAC81313 EAW58370 Q9Y3P8 AA310964 AA746595 AJ010059 CAB41504 AK314758 BAG37296 BC102029 AAI02030 BC104491 AAI04492 BC107484 AAI07485 BM919490 JQ924063 AFK32776 NM_014450 NP_055265
Function Negatively regulates TCR (T-cell antigen receptor)- mediated signaling in T-cells. Involved in positive selection of T-cells. {ECO:0000269|PubMed:10209036}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:10209036}; Single-pass type I membrane protein {ECO:0000269|PubMed:10209036}.
Tissue Specificity Specifically expressed in T- and B-cells. Present in plasma cells but not in germinal center B-cells (at protein level). Expressed in T- and B-cell lymphoma. {ECO:0000269|PubMed:10209036, ECO:0000269|PubMed:16160011}.

SIT CRISPR/Cas9 KO Plasmid (h) - sc-407786 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SIT HDR Plasmid (h) - sc-407786-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SIT Double Nickase Plasmid (h) - sc-407786-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SIT Double Nickase Plasmid (h2) - sc-407786-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SIT CRISPR Activation Plasmid (h) - sc-407786-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SIT CRISPR Activation Plasmid (h2) - sc-407786-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SIT Lentiviral Activation Particles (h) - sc-407786-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SIT Lentiviral Activation Particles (h2) - sc-407786-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SIT siRNA (h) - sc-45334 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SIT shRNA Plasmid (h) - sc-45334-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SIT shRNA (h) Lentiviral Particles - sc-45334-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN19365 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19365 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04806 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04806

SIT1 siRNA (Human) - CRH9033 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SIT1 - MBS8223719 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SIT1 (NM_014450.2) - SHH407816 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SIT1(NM_014450.2) - SHR226812 from Creative biogene

Category siRNA
Species Reactivities Human

SIT1 shRNA Plasmid (Human) - CHH9033 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SIT1 miRNA 3'UTR clone - MiUTR1H-09415 from Creative biogene

Species Reactivities Human
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