GGH

Gene Symbol	GGH
Entrez Gene	8836
Alt Symbol	GH
Species	Human
Gene Type	protein-coding
Description	gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
Other Description	gamma-Glu-X carboxypeptidase|gamma-glutamyl hydrolase
Swissprots	Q92820
Accessions	AAF03360 EAW86862 Q92820 AK290450 BAF83139 AK301094 BAG62694 BC025025 AAH25025 JF432643 ADZ15860 U55206 AAC05579 XM_011517623 XP_011515925 NM_003878 NP_003869
Function	Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha- glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates.
Subcellular Location	Secreted, extracellular space. Lysosome. Melanosome. Note=While its intracellular location is primarily the lysosome, most of the enzyme activity is secreted. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Top Pathways	Folate biosynthesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GGH gene - orb92081 from Biorbyt Prices $306.00 Sizes 10 μg Species Human

Human-GGH-cDNA-Clone - DC05448 from Abgent, a WuXi AppTec company Prices $429.30 Sizes 10 µg Species Human Accession BC025025

GGH - MBS1270685 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC025025

Human GGH ORF clone(NM_003878.2) - CDCL184402 from Creative Biomart Species Human Accession NM_003878.2

Human GGH ORF Clone(NM_003878.2) - CDCL164580 from Creative Biomart Species Human Accession NM_003878.2

Human GGH/Glutamyl hydrolase gamma Gene ORF cDNA clone in cloning vector - HG12068-G from Sino Biological Species Human

Human GGH/Glutamyl hydrolase gamma Gene ORF cDNA clone expression plasmid, N-HA tag - HG12068-NY from Sino Biological Species Human

Human GGH/Glutamyl hydrolase gamma Gene ORF cDNA clone expression plasmid, N-His tag - HG12068-NH from Sino Biological Species Human

Human GGH/Glutamyl hydrolase gamma Gene ORF cDNA clone expression plasmid, N-Flag tag - HG12068-NF from Sino Biological Species Human

Human GGH/Glutamyl hydrolase gamma Gene ORF cDNA clone expression plasmid, N-Myc tag - HG12068-NM from Sino Biological Species Human

Human GGH/Glutamyl hydrolase gamma Gene ORF cDNA clone expression plasmid, C-Flag tag - HG12068-CF from Sino Biological Species Human

Human GGH/Glutamyl hydrolase gamma Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG12068-ACR from Sino Biological Species Human

Human GGH/Glutamyl hydrolase gamma Gene ORF cDNA clone expression plasmid, C-His tag - HG12068-CH from Sino Biological Species Human

Human GGH/Glutamyl hydrolase gamma Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG12068-ACG from Sino Biological Species Human

Human GGH/Glutamyl hydrolase gamma Gene ORF cDNA clone expression plasmid, C-Myc tag - HG12068-CM from Sino Biological Species Human

Human GGH/Glutamyl hydrolase gamma Gene ORF cDNA clone expression plasmid, C-HA tag - HG12068-CY from Sino Biological Species Human

Human GGH/Glutamyl hydrolase gamma Gene ORF cDNA clone expression plasmid - HG12068-G-N from Sino Biological Species Human

Human GGH/Glutamyl hydrolase gamma Gene ORF cDNA clone expression plasmid - HG12068-UT from Sino Biological Species Human

Human GGH ORF clone(NM_003878.2) - CDCL184402 from Creative biogene Species Human

Human GGH ORF Clone (BC025025) - CDCS411522 from Creative biogene Species Human Accession Q92820

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