GGH

Gene Symbol	GGH
Entrez Gene	8836
Alt Symbol	GH
Species	Human
Gene Type	protein-coding
Description	gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
Other Description	gamma-Glu-X carboxypeptidase|gamma-glutamyl hydrolase
Swissprots	Q92820
Accessions	AAF03360 EAW86862 Q92820 AK290450 BAF83139 AK301094 BAG62694 BC025025 AAH25025 JF432643 ADZ15860 U55206 AAC05579 XM_011517623 XP_011515925 NM_003878 NP_003869
Function	Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha- glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates.
Subcellular Location	Secreted, extracellular space. Lysosome. Melanosome. Note=While its intracellular location is primarily the lysosome, most of the enzyme activity is secreted. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Top Pathways	Folate biosynthesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Glutamyl hydrolase gamma full length protein - ab123172 from Abcam Category Protein Source E. coli Species Human

gamma-glutamyl hydrolase Recombinant Protein - H00008836-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human gamma-glutamyl hydrolase Protein - NBP1-78898 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

GGH-Antibody-N-term-Blocking-peptide - BP11236a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GGH-Antibody-C-term-Blocking-peptide - BP12045b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human GGH protein - orb168390 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

Gamma-glutamyl hydrolase / GGH (25-318, His-tag) - AR50224PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

Gamma-glutamyl hydrolase / GGH (25-318, His-tag) - AR50224PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

Gamma-glutamyl hydrolase / GGH - H00008836-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Gamma-glutamyl hydrolase / GGH - H00008836-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Gamma-Glutamyl Hydrolase, Human Recombinant - 228-12393-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Gamma-Glutamyl Hydrolase Human - 228-12393-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source E.coli. Species Human

Recombinant Gamma-Glutamyl Hydrolase Human - 228-12393-3 from RayBiotech Category Protein Prices $2,880.00 Sizes 3 µg Source E.coli. Species Human

GGH, 25-318aa, Human, His tag, E.coli - 01-P1399 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

GGH fusion protein - Ag3939 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

GGH Human - ENPS-249 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source E.coli. Species Human

Recombinant Human GGCT Enzyme - BP000930-ENZ-062 from Syd Labs Category Protein Prices $160.00, $2,700.00 Sizes 20 µg, 1 mg Source E. coli-derived. Species Human

GGH, 25-318aa, Recombinant Protein - GWB-P0639B from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 100 μg, 500 μg Source E.coli Species Human

Recombinant Human GGH, GST-tagged - GGH-13241H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Gamma-Glutamyl Hydrolase (conjugase, folylpolygammaglutamyl hydrolase), His-tagged - GGH-1399H from Creative Biomart Category Protein

GGH 25-318aa - CMB-1232 from Reagent Proteins Category Protein Prices $469.00, $889.00 Sizes 100.00 µg, 500 µg Source E.coli Species Human

Recombinant Gamma-Glutamyl Hydrolase (gGH) - RPJ038Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

GGH (K287) Peptide - BS3864P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Gamma-glutamyl hydrolase(GGH) - CSB-YP852914HU CSB-EP852914HU CSB-BP852914HU CSB-MP852914HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

GGH, 25-318aa, Human, His tag, E.coli - ATGP1399 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

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