MKNK1

Gene Symbol	MKNK1
Entrez Gene	8569
Alt Symbol	MNK1
Species	Human
Gene Type	protein-coding
Description	MAP kinase interacting serine/threonine kinase 1
Other Description	MAP kinase signal-integrating kinase 1|MAP kinase-interacting serine/threonine-protein kinase 1|MAPK signal-integrating kinase 1
Swissprots	D3DQ21 Q5TC07 O00312 Q6V0N6 Q5TC06 D3DQ20 Q9BUB5
Accessions	EAX06900 EAX06901 EAX06902 EAX06903 EAX06904 EAX06905 Q9BUB5 AB000409 BAA19885 AB451300 BAG70114 AB451432 BAG70246 AK096423 BAG53286 AK290456 BAF83145 AK298839 BAG60967 AK304005 BAG64921 AK310566 AY355461 AAQ84219 BC002755 AAH02755 BG722049 BM665342 BX538193 CAD98062 BX648559 DA435648 DA502363 DC366212 DC376088 DQ892992 ABM83918 DQ896240 ABM87239 EU831624 ACE87224 EU831709 ACE86543 XM_006710999 XP_006711062 XM_006711000 XP_006711063 XM_006711001 XP_006711064 XM_006711002 XP_006711065 XM_006711003 XP_006711066 XM_006711004 XP_006711067 XM_006711005 XP_006711068 XM_006711006 XP_006711069 XM_006711007 XP_006711070 XM_006711008 XP_006711071 XM_006711009 XP_006711072 XM_006711010 XP_006711073 XM_006711013 XP_006711076 XM_006711014 XP_006711077 XM_006711015 XP_006711078 XM_011542349 XP_011540651 XM_011542350 XP_011540652 NM_001135553 NP_001129025 NM_003684 NP_003675 NM_198973 NP_945324 NR_024174 NR_024176 NR_024175
Function	May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7- methylguanosine-containing mRNA cap. {ECO:0000269|PubMed:11463832, ECO:0000269|PubMed:15350534, ECO:0000269|PubMed:9155018, ECO:0000269|PubMed:9878069}.
Subcellular Location	Isoform 2: Cytoplasm.
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:15350534}.
Top Pathways	Insulin signaling pathway, MAPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MKNK1-Over-expression-Lysate - LY10344a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

MKNK1 overexpression lysate - LY418502 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

MKNK1 overexpression lysate - LY427613 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

MKNK1 293 Cell Lysate - 408631 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

MNK1 Overexpression Lysate (Native) - NBL1-13123 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Mnk1 (h): 293T Lysate - sc-171267 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

Mnk1 (h2): 293 Lysate - sc-172000 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

Mnk1 (h3): 293 Lysate - sc-177561 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

MKNK1 Over-expression Lysate Product - GWB-C3E502 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human MKNK1 Knockdown Stable Cell Line - CSC-DC009546 from Creative biogene Category Cell Line Species Human

Human MKNK1 Knockout Cell Line-HeLa - CSC-RT1482 from Creative biogene Category Cell Line Species Human

MKNK1 KO Cell Lysate-HeLa - CLKO-1332 from Creative biogene Category Cell Lysate

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