MKNK1

Gene Symbol	MKNK1
Entrez Gene	8569
Alt Symbol	MNK1
Species	Human
Gene Type	protein-coding
Description	MAP kinase interacting serine/threonine kinase 1
Other Description	MAP kinase signal-integrating kinase 1|MAP kinase-interacting serine/threonine-protein kinase 1|MAPK signal-integrating kinase 1
Swissprots	D3DQ21 Q5TC07 O00312 Q6V0N6 Q5TC06 D3DQ20 Q9BUB5
Accessions	EAX06900 EAX06901 EAX06902 EAX06903 EAX06904 EAX06905 Q9BUB5 AB000409 BAA19885 AB451300 BAG70114 AB451432 BAG70246 AK096423 BAG53286 AK290456 BAF83145 AK298839 BAG60967 AK304005 BAG64921 AK310566 AY355461 AAQ84219 BC002755 AAH02755 BG722049 BM665342 BX538193 CAD98062 BX648559 DA435648 DA502363 DC366212 DC376088 DQ892992 ABM83918 DQ896240 ABM87239 EU831624 ACE87224 EU831709 ACE86543 XM_006710999 XP_006711062 XM_006711000 XP_006711063 XM_006711001 XP_006711064 XM_006711002 XP_006711065 XM_006711003 XP_006711066 XM_006711004 XP_006711067 XM_006711005 XP_006711068 XM_006711006 XP_006711069 XM_006711007 XP_006711070 XM_006711008 XP_006711071 XM_006711009 XP_006711072 XM_006711010 XP_006711073 XM_006711013 XP_006711076 XM_006711014 XP_006711077 XM_006711015 XP_006711078 XM_011542349 XP_011540651 XM_011542350 XP_011540652 NM_001135553 NP_001129025 NM_003684 NP_003675 NM_198973 NP_945324 NR_024174 NR_024176 NR_024175
Function	May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7- methylguanosine-containing mRNA cap. {ECO:0000269|PubMed:11463832, ECO:0000269|PubMed:15350534, ECO:0000269|PubMed:9155018, ECO:0000269|PubMed:9878069}.
Subcellular Location	Isoform 2: Cytoplasm.
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:15350534}.
Top Pathways	Insulin signaling pathway, MAPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human MNK1 full length protein - ab125635 from Abcam Category Protein Prices $239.00 Sizes 5 µg Source Baculovirus infected sf9 cells Species Human

Human MNK1 full length protein - ab152892 from Abcam Category Protein Source Wheat germ Species Human

Human MNK1 full length protein - ab62572 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

Human MNK1 protein fragment - ab152893 from Abcam Category Protein Source Wheat germ Species Human

MKNK1 / MNK1 Antibody Blocking Peptide - LS-E8723 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MKNK1 / MNK1 Antibody Blocking Peptide - LS-E22086 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MKNK1 / MNK1 Antibody Blocking Peptide - LS-E22085 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human MNK1 Protein - H00008569-P01 from Novus Biologicals Category Protein Prices $319.00, $369.00, $529.00 Sizes 2 µg, 10 µg, 25 µg Source Wheat Germ Species Human

MNK1 Partial Recombinant Protein - H00008569-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

MNK1 Peptide - P2306 from Novus Biologicals Category Peptide Species Human

MKNK1-Antibody-N-term-Blocking-Peptide - BP7151a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MKNK1 Blocking Peptide - 33R-1781 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MKNK1 Blocking Peptide - 33R-3715 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MKNK1 - H00008569-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MKNK1 - H00008569-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MKNK1 - H00008569-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MKNK1 - H00008569-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MKNK1 - P5601 from Acris Antibodies Category Protein Prices $840.00 Sizes 5 µg Species Human

MKNK1 fusion protein - ag0184 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

MNK1 (5385D), Active Human Recombinant Protein - GWB-18F7F0 from Genway Biotech Category Protein Prices $410.00 Sizes 10 µg Species Human

Recombinant Human MKNK1 - MKNK1-28176TH from Creative Biomart Category Protein

Recombinant Human MKNK1, GST-tagged - MKNK1-519H from Creative Biomart Category Protein Source Sf9 .

Recombinant Human MAP Kinase Interacting Serine/Threonine Kinase 1, GST-tagged - MKNK1-1061H from Creative Biomart Category Protein Species Human

Mnk1 (I136) Peptide - BS2133P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human MAP kinase-interacting serine/threonine-protein kinase 1(MKNK1) - CSB-YP861139HU CSB-EP861139HU CSB-BP861139HU CSB-MP861139HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

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