MKNK1

Gene Symbol	MKNK1
Entrez Gene	8569
Alt Symbol	MNK1
Species	Human
Gene Type	protein-coding
Description	MAP kinase interacting serine/threonine kinase 1
Other Description	MAP kinase signal-integrating kinase 1|MAP kinase-interacting serine/threonine-protein kinase 1|MAPK signal-integrating kinase 1
Swissprots	D3DQ21 Q5TC07 O00312 Q6V0N6 Q5TC06 D3DQ20 Q9BUB5
Accessions	EAX06900 EAX06901 EAX06902 EAX06903 EAX06904 EAX06905 Q9BUB5 AB000409 BAA19885 AB451300 BAG70114 AB451432 BAG70246 AK096423 BAG53286 AK290456 BAF83145 AK298839 BAG60967 AK304005 BAG64921 AK310566 AY355461 AAQ84219 BC002755 AAH02755 BG722049 BM665342 BX538193 CAD98062 BX648559 DA435648 DA502363 DC366212 DC376088 DQ892992 ABM83918 DQ896240 ABM87239 EU831624 ACE87224 EU831709 ACE86543 XM_006710999 XP_006711062 XM_006711000 XP_006711063 XM_006711001 XP_006711064 XM_006711002 XP_006711065 XM_006711003 XP_006711066 XM_006711004 XP_006711067 XM_006711005 XP_006711068 XM_006711006 XP_006711069 XM_006711007 XP_006711070 XM_006711008 XP_006711071 XM_006711009 XP_006711072 XM_006711010 XP_006711073 XM_006711013 XP_006711076 XM_006711014 XP_006711077 XM_006711015 XP_006711078 XM_011542349 XP_011540651 XM_011542350 XP_011540652 NM_001135553 NP_001129025 NM_003684 NP_003675 NM_198973 NP_945324 NR_024174 NR_024176 NR_024175
Function	May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7- methylguanosine-containing mRNA cap. {ECO:0000269|PubMed:11463832, ECO:0000269|PubMed:15350534, ECO:0000269|PubMed:9155018, ECO:0000269|PubMed:9878069}.
Subcellular Location	Isoform 2: Cytoplasm.
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:15350534}.
Top Pathways	Insulin signaling pathway, MAPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MKNK1 ORF clone(NM_003684.5) - CDCH390095 from Creative Biomart Species Human Accession NM_003684.5

Human MKNK1 ORF Clone(NM_001135553.2) - CDCL170182 from Creative Biomart Species Human Accession NM_001135553.2

Human MKNK1 ORF Clone(NM_001135553.2) - CDCL170183 from Creative Biomart Species Human Accession NM_001135553.2

Human MKNK1 transcript variant 2 Gene ORF cDNA clone in cloning vector - HG10038-M from Sino Biological Species Human

Human MKNK1 transcript variant 2 Gene ORF cDNA clone expression plasmid - HG10038-UT from Sino Biological Species Human

Human MKNK1 transcript variant 2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10038-NY from Sino Biological Species Human

Human MKNK1 transcript variant 2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10038-NF from Sino Biological Species Human

Human MKNK1 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10038-ACG from Sino Biological Species Human

Human MKNK1 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10038-CF from Sino Biological Species Human

Human MKNK1 transcript variant 2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10038-NM from Sino Biological Species Human

Human MKNK1 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10038-CM from Sino Biological Species Human

Human MKNK1 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10038-M-F from Sino Biological Species Human

Human MKNK1 transcript variant 2 Gene ORF cDNA clone expression plasmid, N-His tag - HG10038-NH from Sino Biological Species Human

Human MKNK1 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10038-ACR from Sino Biological Species Human

Human MKNK1 transcript variant 2 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG10038-ANR from Sino Biological Species Human

Human MKNK1 transcript variant 2 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG10038-ANG from Sino Biological Species Human

Human MKNK1 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10038-CY from Sino Biological Species Human

Human MKNK1 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-His tag - HG10038-CH from Sino Biological Species Human

Human MKNK1 ORF clone(NM_003684.5) - CDCH390095 from Creative biogene Species Human

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