MKNK1

Gene Symbol MKNK1
Entrez Gene 8569
Alt Symbol MNK1
Species Human
Gene Type protein-coding
Description MAP kinase interacting serine/threonine kinase 1
Other Description MAP kinase signal-integrating kinase 1|MAP kinase-interacting serine/threonine-protein kinase 1|MAPK signal-integrating kinase 1
Swissprots D3DQ21 Q5TC07 O00312 Q6V0N6 Q5TC06 D3DQ20 Q9BUB5
Accessions EAX06900 EAX06901 EAX06902 EAX06903 EAX06904 EAX06905 Q9BUB5 AB000409 BAA19885 AB451300 BAG70114 AB451432 BAG70246 AK096423 BAG53286 AK290456 BAF83145 AK298839 BAG60967 AK304005 BAG64921 AK310566 AY355461 AAQ84219 BC002755 AAH02755 BG722049 BM665342 BX538193 CAD98062 BX648559 DA435648 DA502363 DC366212 DC376088 DQ892992 ABM83918 DQ896240 ABM87239 EU831624 ACE87224 EU831709 ACE86543 XM_006710999 XP_006711062 XM_006711000 XP_006711063 XM_006711001 XP_006711064 XM_006711002 XP_006711065 XM_006711003 XP_006711066 XM_006711004 XP_006711067 XM_006711005 XP_006711068 XM_006711006 XP_006711069 XM_006711007 XP_006711070 XM_006711008 XP_006711071 XM_006711009 XP_006711072 XM_006711010 XP_006711073 XM_006711013 XP_006711076 XM_006711014 XP_006711077 XM_006711015 XP_006711078 XM_011542349 XP_011540651 XM_011542350 XP_011540652 NM_001135553 NP_001129025 NM_003684 NP_003675 NM_198973 NP_945324 NR_024174 NR_024176 NR_024175
Function May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7- methylguanosine-containing mRNA cap. {ECO:0000269|PubMed:11463832, ECO:0000269|PubMed:15350534, ECO:0000269|PubMed:9155018, ECO:0000269|PubMed:9878069}.
Subcellular Location Isoform 2: Cytoplasm.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:15350534}.
Top Pathways Insulin signaling pathway, MAPK signaling pathway

Mnk1 CRISPR/Cas9 KO Plasmid (h) - sc-402417 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mnk1 HDR Plasmid (h) - sc-402417-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mnk1 Double Nickase Plasmid (h) - sc-402417-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mnk1 Double Nickase Plasmid (h2) - sc-402417-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mnk1 CRISPR Activation Plasmid (h) - sc-402417-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mnk1 CRISPR Activation Plasmid (h2) - sc-402417-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mnk1 Lentiviral Activation Particles (h) - sc-402417-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mnk1 Lentiviral Activation Particles (h2) - sc-402417-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mnk1 siRNA (h) - sc-39106 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Mnk1 shRNA Plasmid (h) - sc-39106-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Mnk1 shRNA (h) Lentiviral Particles - sc-39106-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MNK1 RNAi - H00008569-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MNK1 RNAi - H00008569-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU115211 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK1300 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK1302 from Sigma-Aldrich

Category siRNA

MISSION® siRNA - SIHK1303 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK1299 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK1301 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN14381 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14381 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08967 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08967

MKNK1 siRNA (Human) - CRH5637 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MKNK1 (NM_003684.5) - SHH342308 from Creative biogene

Category siRNA
Species Reactivities Human

Human MKNK1 siRNA - orb266139 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human
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