TEAD4

Gene Symbol TEAD4
Entrez Gene 7004
Alt Symbol EFTR-2, RTEF1, TCF13L1, TEF-3, TEF3, TEFR-1, hRTEF-1B
Species Human
Gene Type protein-coding
Description TEA domain family member 4
Other Description related transcription enhancer factor 1B|transcription factor 13-like 1|transcription factor RTEF-1|transcriptional enhancer factor 1-related|transcriptional enhancer factor 3|transcriptional enhancer factor TEF-3
Swissprots Q6MZR9 Q96BK2 Q92883 Q15561 H0Y308 Q8NEV5
Accessions EAW88872 EAW88873 EAW88874 EAW88875 Q15561 AK222947 BAD96667 AY101179 AAM89497 BC015497 AAH15497 BM464237 BM555991 BX640921 CAE45959 DA210894 DA886817 EU446502 ABZ92031 U63824 AAC50763 X94438 CAA64212 NM_003213 NP_003204 NM_201441 NP_958849 NM_201443 NP_958851
Function Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif. {ECO:0000269|PubMed:18579750, ECO:0000269|PubMed:19324877}.
Subcellular Location Nucleus.
Tissue Specificity Preferentially expressed in skeletal muscle. Lower levels in pancreas, placenta, and heart.
Top Pathways Hippo signaling pathway

Transcriptional enhancer factor TEF-3 (TEAD4), Human, ELISA Kit - E01T0675 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

TEAD4 (Human) IP-WB Antibody Pair - H00007004-PW1 from Acris Antibodies

Category Antibody Pair
Prices $610.00
Sizes 1 set

TEAD4 (Human) Matched Antibody Pair - H00007004-AP51 from Acris Antibodies

Category Antibody Pair
Prices $610.00
Sizes 1 set

Transcriptional enhancer factor TEF 3 (TEAD4), ELISA Kit - MBS7236174 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional enhancer factor TEF-3 (TEAD4), ELISA Kit - MBS7252992 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional enhancer factor TEF-3 (TEAD4), ELISA Kit - MBS7233303 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional enhancer factor TEF-3 (TEAD4), ELISA Kit - MBS7225940 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional enhancer factor TEF-3 (TEAD4), ELISA Kit - MBS7207010 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional enhancer factor TEF-3 (TEAD4), ELISA Kit - MBS7220611 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional enhancer factor TEF-3 (TEAD4), ELISA Kit - MBS7241387 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional enhancer factor TEF-3 (TEAD4), ELISA Kit - MBS7207864 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional enhancer factor TEF-3 (TEAD4), ELISA Kit - MBS7204545 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional enhancer factor TEF-3 (TEAD4), ELISA Kit - MBS7222769 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional enhancer factor TEF-3 (TEAD4), ELISA Kit - MBS7202299 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human TEAD4 ELISA Kit - E038875 from Biobool

Category ELISA Kit
Search more