PFN2

Gene Symbol	PFN2
Entrez Gene	5217
Alt Symbol	D3S1319E, PFL
Species	Human
Gene Type	protein-coding
Description	profilin 2
Other Description	profilin II|profilin-2
Swissprots	Q8WVF9 D3DNI4 Q9HBK2 B2R4C8 P35080 Q4VBQ4
Accessions	EAW78850 EAW78851 EAW78852 EAW78853 EAW78854 EAW78855 EAW78856 P35080 AF228738 AAG24949 AK297915 BAG60233 AK307227 AK311780 BAG34723 AK311782 BAG34725 AL096719 BC002964 BC018049 AAH18049 BC043646 AAH43646 BC095444 AAH95444 BX463350 EU832616 ACE87707 EU832688 ACE87020 L10678 AAA03022 NM_002628 NP_002619 NM_053024 NP_444252
Function	Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
Subcellular Location	Cytoplasm, cytoskeleton.
Tissue Specificity	Highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver.
Top Pathways	Salmonella infection, Rap1 signaling pathway, Regulation of actin cytoskeleton

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Profilin-2 (4K-6) - sc-100955 from Santa Cruz Biotechnology Prices $295.00 Sizes 100 µg/ml Host Mouse Clonality Monoclonal

Anti-Profilin 2 antibody - ab14251 from Abcam Prices $406.00 Sizes 50 µg Host Chicken Clonality Polyclonal

Anti-Profilin 2 antibody - ab96676 from Abcam Prices $370.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

Anti-Profilin 2 antibody - ab55611 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-Profilin 2 antibody - ab123871 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-Profilin 2 antibody [EPR11030] - ab174322 from Abcam Prices $357.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR11030

Anti-PFN2 / Profilin 2 Antibody (clone 6G3) - LS-C139402 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 6G3

Anti-PFN2 / Profilin 2 Antibody (aa110-139) - LS-C163537 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-PFN2 / Profilin 2 Antibody (aa5-140) - LS-C296042 from LifeSpan Bioscience Prices $405.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-PFN2 / Profilin 2 Antibody (aa1-90) - LS-C186004 from LifeSpan Bioscience Prices $335.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-PFN2 / Profilin 2 Antibody - LS-C89300 from LifeSpan Bioscience Prices $650.00 Sizes 50 µg Host Chicken Clonality Polyclonal

Anti-PFN2 / Profilin 2 Antibody (aa109-139, AP) - LS-C266086 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PFN2 / Profilin 2 Antibody (aa109-139, APC) - LS-C266087 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PFN2 / Profilin 2 Antibody (aa109-139, FITC) - LS-C266089 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PFN2 / Profilin 2 Antibody (aa109-139, Biotin) - LS-C266088 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PFN2 / Profilin 2 Antibody (aa109-139, Azide-free, HRP) - LS-C266090 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PFN2 / Profilin 2 Antibody (aa5-140, Biotin) - LS-C299836 from LifeSpan Bioscience Prices $435.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-PFN2 / Profilin 2 Antibody (aa5-140, FITC) - LS-C302186 from LifeSpan Bioscience Prices $455.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-PFN2 / Profilin 2 Antibody (aa109-139, PE) - LS-C284535 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PFN2 / Profilin 2 Antibody (aa125-140) - LS-C313269 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-PFN2 / Profilin 2 Antibody (aa109-139) - LS-C323953 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PFN2 / Profilin 2 Antibody - LS-C314053 from LifeSpan Bioscience Prices $385.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-PFN2 / Profilin 2 Antibody (aa41-141, Azide-free) - LS-C328313 from LifeSpan Bioscience Host Mouse Clonality Monoclonal

Profilin 2 Antibody - NBP1-87426 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Profilin 2 Antibody - NBP1-31629 from Novus Biologicals Prices $349.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

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