PFN2

Gene Symbol	PFN2
Entrez Gene	5217
Alt Symbol	D3S1319E, PFL
Species	Human
Gene Type	protein-coding
Description	profilin 2
Other Description	profilin II|profilin-2
Swissprots	Q8WVF9 D3DNI4 Q9HBK2 B2R4C8 P35080 Q4VBQ4
Accessions	EAW78850 EAW78851 EAW78852 EAW78853 EAW78854 EAW78855 EAW78856 P35080 AF228738 AAG24949 AK297915 BAG60233 AK307227 AK311780 BAG34723 AK311782 BAG34725 AL096719 BC002964 BC018049 AAH18049 BC043646 AAH43646 BC095444 AAH95444 BX463350 EU832616 ACE87707 EU832688 ACE87020 L10678 AAA03022 NM_002628 NP_002619 NM_053024 NP_444252
Function	Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
Subcellular Location	Cytoplasm, cytoskeleton.
Tissue Specificity	Highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver.
Top Pathways	Salmonella infection, Rap1 signaling pathway, Regulation of actin cytoskeleton

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-PFN2-cDNA-Clone - DC04648 from Abgent, a WuXi AppTec company Prices $189.00 Sizes 10 µg Species Human Accession BC018049

PFN2 - MBS1276793 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC018049

Human Profilin 2 / PFN2 Gene ORF cDNA clone in cloning vector - HG14496-G from Sino Biological Species Human

Human Profilin 2 / PFN2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG14496-CY from Sino Biological Species Human

Human Profilin 2 / PFN2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14496-NF from Sino Biological Species Human

Human Profilin 2 / PFN2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14496-CF from Sino Biological Species Human

Human Profilin 2 / PFN2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14496-NM from Sino Biological Species Human

Human Profilin 2 / PFN2 Gene ORF cDNA clone expression plasmid, N-His tag - HG14496-NH from Sino Biological Species Human

Human Profilin 2 / PFN2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14496-CM from Sino Biological Species Human

Human Profilin 2 / PFN2 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG14496-ANG from Sino Biological Species Human

Human Profilin 2 / PFN2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG14496-NY from Sino Biological Species Human

Human Profilin 2 / PFN2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14496-ACG from Sino Biological Species Human

Human Profilin 2 / PFN2 Gene ORF cDNA clone expression plasmid, C-His tag - HG14496-CH from Sino Biological Species Human

Human Profilin 2 / PFN2 Gene ORF cDNA clone expression plasmid - HG14496-UT from Sino Biological Species Human

Human Profilin 2 / PFN2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14496-ACR from Sino Biological Species Human

Human Profilin 2 / PFN2 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG14496-ANR from Sino Biological Species Human

Human PFN2 ORF Clone (BC018049) - CDCS410880 from Creative biogene Species Human Accession P35080

Human PFN2 ORF clone (BC018049) - CDCB159072 from Creative biogene Species Human

Human PFN2 cDNA Clone - orb144716 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

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