PFN2

Gene Symbol	PFN2
Entrez Gene	5217
Alt Symbol	D3S1319E, PFL
Species	Human
Gene Type	protein-coding
Description	profilin 2
Other Description	profilin II|profilin-2
Swissprots	Q8WVF9 D3DNI4 Q9HBK2 B2R4C8 P35080 Q4VBQ4
Accessions	EAW78850 EAW78851 EAW78852 EAW78853 EAW78854 EAW78855 EAW78856 P35080 AF228738 AAG24949 AK297915 BAG60233 AK307227 AK311780 BAG34723 AK311782 BAG34725 AL096719 BC002964 BC018049 AAH18049 BC043646 AAH43646 BC095444 AAH95444 BX463350 EU832616 ACE87707 EU832688 ACE87020 L10678 AAA03022 NM_002628 NP_002619 NM_053024 NP_444252
Function	Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
Subcellular Location	Cytoplasm, cytoskeleton.
Tissue Specificity	Highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver.
Top Pathways	Salmonella infection, Rap1 signaling pathway, Regulation of actin cytoskeleton

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Profilin 2 full length protein - ab185845 from Abcam Category Protein Source E. coli Species Human

Human Profilin 2 full length protein - ab40202 from Abcam Category Protein Source E. coli Species Human

Human Profilin 2 full length protein - ab95291 from Abcam Category Protein Source E. coli Species Human

PFN2 / Profilin 2 Antibody Blocking Peptide - LS-E3822 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Profilin 2 Partial Recombinant Protein - H00005217-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Profilin 2 Protein - NBP1-44493 from Novus Biologicals Category Protein Prices $269.00 Sizes 50 µg Source E. coli Species Human

Profilin 2 Recombinant Protein - H00005217-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg

PFN2-Antibody-C-term-Blocking-Peptide - BP16001b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Profilin 2 Protein - GTX108589-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

PFN2 Protein (OPPA02346) - OPPA02346 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Human PFN2 protein (His Tag) - orb139478 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source E. coli Species Human

Human PFN2 protein - orb81271 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

Human PFN2 protein - orb180379 from Biorbyt Category Protein Prices $204.00, $323.00, $1,411.00, $1,981.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

PFN2 protein (His tag) - 80R-1300 from Fitzgerald Category Protein Prices $255.00 Sizes 50 µg Source E.coli

Human Profilin 2 Protein - abx068677 from Abbexa Category Protein Source E.coli Species Human

Profilin 2 Blocking Peptide - abx063073 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Monkey

Profilin 2 (PFN2) (1-140, His-tag) - AR09443PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

Profilin 2 (PFN2) (1-140, His-tag) - AR09443PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

Profilin 2 (PFN2) - H00005217-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Profilin 2 (PFN2) - H00005217-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Profilin 2 (PFN2) - H00005217-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Profilin 2 (PFN2) - H00005217-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Profilin-2, Human Recombinant - 228-13250-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Human Profilin-2 - 228-13250-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human Profilin-2 - 228-13250-3 from RayBiotech Category Protein Source Escherichia Coli. Species Human

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