WAS

Gene Symbol WAS
Entrez Gene 7454
Alt Symbol IMD2, SCNX, THC, THC1, WASP, WASPA
Species Human
Gene Type protein-coding
Description Wiskott-Aldrich syndrome
Other Description eczema-thrombocytopenia|thrombocytopenia 1 (X-linked)|wiskott-Aldrich syndrome protein
Swissprots Q9UNJ9 Q9BU11 P42768
Accessions AAA60381 AAD26691 CAJ30264 EAW50758 EAW50759 P42768 BC002961 AAH02961 BC012738 AAH12738 BI910072 CF529565 EU176449 ABW03900 U12707 AAA62663 U19927 AAC50140 XM_011543977 XP_011542279 NM_000377 NP_000368
Function Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria. {ECO:0000269|PubMed:12235133, ECO:0000269|PubMed:16275905, ECO:0000269|PubMed:18650809}.
Subcellular Location Cytoplasm, cytoskeleton.
Tissue Specificity Expressed predominantly in the thymus. Also found, to a much lesser extent, in the spleen. {ECO:0000269|PubMed:8069912}.
Top Pathways Fc gamma R-mediated phagocytosis, Choline metabolism in cancer, Salmonella infection, Bacterial invasion of epithelial cells, Chemokine signaling pathway

WASP Antibody - 4860 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines, using WASP Antibody.

WASP (D9C8) Rabbit mAb - 4271 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D9C8
Western blot analysis of extracts from Jurkat, Raji and Ramos cells using WASP (D9C8) Rabbit mAb.

WASP (B-12) - sc-398477 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
WASP (B-12): sc-398477. Western blot analysis of WASP expression in BJAB whole cell lysate.

WASP (F-8) - sc-365859 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
WASP (F-8): sc-365859. Western blot analysis of WASP expression in BJAB (A) and Ramos (B) whole cell lysates.

WASP (H-250) - sc-8353 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
WASP (H-250): sc-8353. Western blot analysis of WASP expression in BJAB (A) and MOLT-4 (B) whole cell lysates.

WASP (L-17) - sc-27457 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

WASP (N-20) - sc-9353 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
WASP (N-20): sc-9353. Western blot analysis of WASP expression in BJAB (A) and MOLT-4 (B) whole cell lysates.

WASP (D-15) - sc-30477 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
WASP (D-15): sc-30477. Western blot analysis of WASP expression in Mv 1 Lu (A), Ramos (B) and MOLT-4 (C) whole cell lysates.

WASP (P-15) - sc-30478 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

WASP (Q-13) - sc-27458 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

WASP (B-9) - sc-13139 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
WASP (B-9): sc-13139. Western blot analysis of WASP expression in DT40 (A), Mv 1 Lu (B), KNRK (C) and Ramos (D) whole cell lysates.

WASP (D-1) - sc-5300 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
WASP (D-1): sc-5300. Western blot analysis of WASP expression in MOLT-4 (A), BJAB (B) and Ramos (C) whole cell lysates.

WASP (A-14) - sc-30476 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
WASP (A-14): sc-30476. Western blot analysis of WASP expression in Raji whole cell lysate.

Anti-THC antibody - ab30792 from Abcam

Prices $370.00
Sizes 100 µl
Host Sheep
Clonality Polyclonal

Anti-THC antibody [C29] - ab20867 from Abcam

Prices $370.00
Sizes 500 µg
Host Mouse
Clonality Monoclonal
Clone C29

Anti-WASP antibody - ab180816 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of rat kidney tissue labelling WASP with ab180816 at 1/100. Magnification: 200x.

Anti-WASP antibody [7B10E4] - ab202025 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 7B10E4
Anti-WASP antibody [7B10E4] (ab202025) at 1/500 dilution + Human WASP (aa: 57-170) recombinant protein at 1 µg

Anti-WASP antibody [EP2541Y] - ab75830 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP2541Y
All lanes : Anti-WASP antibody [EP2541Y] (ab75830) at 1/50000 dilutionLane 1 : TF-1 cell lysateLane 2 : U937 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-WASP antibody [EPR2540Y] - ab68182 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR2540Y
All lanes : Anti-WASP antibody [EPR2540Y] (ab68182) at 1/2000 dilutionLane 1 : TF1 cell lysateLane 2 : U937 cell lysateLane 3 : Jurkat cell lysateLysates/proteins at 10 µg per lane.Secondarygoat anti-rabbit HRP at 1/2000 dilution

Anti-WASP antibody [MM0954-34E12] - ab201629 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0954-34E12

Anti-WASP (phospho Y290) antibody - ab59278 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded human brain tissue using ab59278 at a dilution of 1/50. Left image: no immunising peptide. Right hand image: with immunising peptide.

Anti-WASP antibody - ab74904 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-WASP antibody (ab74904) at 1 µg/mlLane 1 : Saos 2 (Human epithelial-like osteosarcoma cell line) Whole Cell LysateLane 2 : LOVO (Human colon adenocarcinoma cell line) Whole Cell LysateLane 3 : HT 1080 (Human fibrosarcoma) Whole Cell LysateLane 4 : EBS E14 TG2A Day 0 (Mouse Pluripotent Embryonic Stem Cell) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-WASP antibody - ab119387 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-WASP antibody (ab119387) at 1/500 dilutionLane 1 : HeLa cell lysateLane 2 : JK cell lysateLane 3 : Raji cell lysate

Anti-WASP antibody - ab59279 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded human brain tissue using ab59279 at a dilution of 1/50. Left hand image - without immunizing peptide; right hand image - with immunizing peptide.

Anti-WASP antibody - ab28769 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-WASP antibody (ab28769) at 0.03 µg/ml + U937 cell lysate (total protein/per lane) at 30 µg/mldeveloped using the ECL technique
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