WAS

Gene Symbol	WAS
Entrez Gene	7454
Alt Symbol	IMD2, SCNX, THC, THC1, WASP, WASPA
Species	Human
Gene Type	protein-coding
Description	Wiskott-Aldrich syndrome
Other Description	eczema-thrombocytopenia|thrombocytopenia 1 (X-linked)|wiskott-Aldrich syndrome protein
Swissprots	Q9UNJ9 Q9BU11 P42768
Accessions	AAA60381 AAD26691 CAJ30264 EAW50758 EAW50759 P42768 BC002961 AAH02961 BC012738 AAH12738 BI910072 CF529565 EU176449 ABW03900 U12707 AAA62663 U19927 AAC50140 XM_011543977 XP_011542279 NM_000377 NP_000368
Function	Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria. {ECO:0000269|PubMed:12235133, ECO:0000269|PubMed:16275905, ECO:0000269|PubMed:18650809}.
Subcellular Location	Cytoplasm, cytoskeleton.
Tissue Specificity	Expressed predominantly in the thymus. Also found, to a much lesser extent, in the spleen. {ECO:0000269|PubMed:8069912}.
Top Pathways	Fc gamma R-mediated phagocytosis, Choline metabolism in cancer, Salmonella infection, Bacterial invasion of epithelial cells, Chemokine signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human WASP peptide - ab42784 from Abcam Category Peptide Species Human

Human WASP peptide - ab74903 from Abcam Category Peptide

Human WASP protein fragment - ab152802 from Abcam Category Protein Source Wheat germ Species Human

WASP peptide (220-232) - ab45709 from Abcam Category Peptide Species Human

WAS / WASP Antibody Blocking Peptide - LS-E6700 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

WAS / WASP Antibody Blocking Peptide - LS-E25843 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

WAS / WASP Antibody Blocking Peptide - LS-E10365 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human WASP Protein - H00007454-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

WAS-AntibodyCenter-Blocking-peptide - BP19544c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

WAS-Antibody-Center-Blocking-Peptide - BP9873c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

WASP blocking peptide - GTX89608-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

Goat anti WAS antibody Immunizing peptide - orb17912 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

WASP Peptide - AC21-0675-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

WAS / IMD2 - H00007454-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

WAS / IMD2 - H00007454-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

WASP Peptide - 46-591P from ProSci Category Peptide Species Human

WAS fusion protein - ag1444 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

WAS fusion protein - Ag23331 from Proteintech Group Category Protein Prices $199.00 Sizes 50 Source E. coli -derived, PET28a Species Human

WASP (E284) Peptide - BS1607P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Wiskott-Aldrich syndrome protein(WAS) - CSB-YP025967HU CSB-EP025967HU CSB-BP025967HU CSB-MP025967HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

WASP / N-WASP - WX2105 from ECM Biosciences Category Peptide Prices $55.00 Sizes 50 μg

WASP (pY290) Blocking Peptide - abx161755 from Abbexa Category Peptide Species Human, Mouse, Rat

Recombinant Wiskott Aldrich Syndrome Protein (WASP) - RPB917Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

WAS / IMD2 - TP303457 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

THC, Recombinant Protein - MBS5303710 from MyBioSource Category Protein Prices $270.00 Sizes 500 µl Source E Coli

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