| Gene Symbol | WAS |
|---|---|
| Entrez Gene | 7454 |
| Alt Symbol | IMD2, SCNX, THC, THC1, WASP, WASPA |
| Species | Human |
| Gene Type | protein-coding |
| Description | Wiskott-Aldrich syndrome |
| Other Description | eczema-thrombocytopenia|thrombocytopenia 1 (X-linked)|wiskott-Aldrich syndrome protein |
| Swissprots | Q9UNJ9 Q9BU11 P42768 |
| Accessions | AAA60381 AAD26691 CAJ30264 EAW50758 EAW50759 P42768 BC002961 AAH02961 BC012738 AAH12738 BI910072 CF529565 EU176449 ABW03900 U12707 AAA62663 U19927 AAC50140 XM_011543977 XP_011542279 NM_000377 NP_000368 |
| Function | Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria. {ECO:0000269|PubMed:12235133, ECO:0000269|PubMed:16275905, ECO:0000269|PubMed:18650809}. |
| Subcellular Location | Cytoplasm, cytoskeleton. |
| Tissue Specificity | Expressed predominantly in the thymus. Also found, to a much lesser extent, in the spleen. {ECO:0000269|PubMed:8069912}. |
| Top Pathways | Fc gamma R-mediated phagocytosis, Choline metabolism in cancer, Salmonella infection, Bacterial invasion of epithelial cells, Chemokine signaling pathway |
Mouse/Human Phospho-WAS / WASP (Tyr290) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1236 from LifeSpan Bioscience
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Wiskott-Aldrich syndrome protein, WAS, Human, ELISA Kit - E1917h from ARP American Research Products
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WASP Colorimetric Cell-Based ELISA Kit - CB5727 from Assay Biotechnology
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WASP (Phospho-Tyr290) Colorimetric Cell-Based ELISA Kit - CBP1231 from Assay Biotechnology
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Wiskott-Aldrich syndrome (eczema-thrombocytopenia) , ELISA Kit - MBS9320844 from MyBioSource
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Wiskott-Aldrich syndrome protein, ELISA Kit - MBS282069 from MyBioSource
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Wiskott-Aldrich syndrome protein (WASP), ELISA Kit - MBS9312992 from MyBioSource
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Wiskott-Aldrich syndrome protein, WASP, ELISA Kit - MBS9301417 from MyBioSource
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Mouse WAS / WASP ELISA Kit (Custom ELISA) - LS-F18811 from LifeSpan Bioscience
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Human WAS / WASP ELISA Kit (Custom ELISA) - LS-F18810 from LifeSpan Bioscience
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Wiskott Aldrich Syndrome Protein (WASP), ELISA Kit - MBS9303387 from MyBioSource
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WASP ELISA Kit - DEIA-XYA1825 from Creative Diagnostics
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WASP (Phospho-Tyr290) ELISA Kit - DEIA-XYA1826 from Creative Diagnostics
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Human WAS ELISA Kit - E040644 from Biobool
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Human WASP ELISA Kit - E040646 from Biobool
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WAS ELISA Kit (Human) (OKEH05298) - OKEH05298 from Aviva Systems Biology
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anti-Wiskott-Aldrich Syndrome / WASP antibody - ARG63714 from Arigo Biolaboratories
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Wiskott-Aldrich syndrome protein, ELISA Kit - MBS2887480 from MyBioSource
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WASP Colorimetric Cell-Based ELISA Kit - EKA50624 from Biomatik
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