WAS

Gene Symbol	WAS
Entrez Gene	7454
Alt Symbol	IMD2, SCNX, THC, THC1, WASP, WASPA
Species	Human
Gene Type	protein-coding
Description	Wiskott-Aldrich syndrome
Other Description	eczema-thrombocytopenia|thrombocytopenia 1 (X-linked)|wiskott-Aldrich syndrome protein
Swissprots	Q9UNJ9 Q9BU11 P42768
Accessions	AAA60381 AAD26691 CAJ30264 EAW50758 EAW50759 P42768 BC002961 AAH02961 BC012738 AAH12738 BI910072 CF529565 EU176449 ABW03900 U12707 AAA62663 U19927 AAC50140 XM_011543977 XP_011542279 NM_000377 NP_000368
Function	Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria. {ECO:0000269|PubMed:12235133, ECO:0000269|PubMed:16275905, ECO:0000269|PubMed:18650809}.
Subcellular Location	Cytoplasm, cytoskeleton.
Tissue Specificity	Expressed predominantly in the thymus. Also found, to a much lesser extent, in the spleen. {ECO:0000269|PubMed:8069912}.
Top Pathways	Fc gamma R-mediated phagocytosis, Choline metabolism in cancer, Salmonella infection, Bacterial invasion of epithelial cells, Chemokine signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-WAS-cDNA-Clone - DC03483 from Abgent, a WuXi AppTec company Prices $677.70 Sizes 10 µg Species Human Accession BC012738

WAS - MBS1267352 from MyBioSource Species Human Accession BC012738

Human WAS Gene ORF cDNA clone in cloning vector - HG14872-G from Sino Biological Species Human

Human WAS Gene ORF cDNA clone expression plasmid, C-His tag - HG14872-CH from Sino Biological Species Human

Human WAS Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14872-ACR from Sino Biological Species Human

Human WAS Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG14872-ANR from Sino Biological Species Human

Human WAS Gene ORF cDNA clone expression plasmid, C-HA tag - HG14872-CY from Sino Biological Species Human

Human WAS Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14872-NF from Sino Biological Species Human

Human WAS Gene ORF cDNA clone expression plasmid - HG14872-UT from Sino Biological Species Human

Human WAS Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14872-CF from Sino Biological Species Human

Human WAS Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14872-ACG from Sino Biological Species Human

Human WAS Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14872-NM from Sino Biological Species Human

Human WAS Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14872-CM from Sino Biological Species Human

Human WAS Gene ORF cDNA clone expression plasmid, N-HA tag - HG14872-NY from Sino Biological Species Human

Human WAS Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG14872-ANG from Sino Biological Species Human

Human WAS Gene ORF cDNA clone expression plasmid, N-His tag - HG14872-NH from Sino Biological Species Human

Human WAS ORF Clone (BC012738) - CDCS419935 from Creative biogene Species Human Accession P42768

Human WAS ORF clone (BC012738) - CDCB158700 from Creative biogene Species Human

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