PLXNB2

Gene Symbol PLXNB2
Entrez Gene 23654
Alt Symbol MM1, Nbla00445, PLEXB2, dJ402G11.3
Species Human
Gene Type protein-coding
Description plexin B2
Other Description plexin-B2
Swissprots Q9BSU7 O15031 Q7KZU3 A6QRH0
Accessions CCF76956 O15031 AB002313 BAA21571 AB075511 BAE45757 AK025415 AK025701 AK056543 AK074932 AK123131 AK126394 BC000221 BC004542 AAH04542 BC110366 AAI10367 BC127770 AAI27771 BC148225 BC148280 BC172440 AAI72440 BT006887 AAP35533 CN388620 S76730 AAB33781 XM_005261909 XP_005261966 XM_005261910 XP_005261967 XM_005261911 XP_005261968 XM_006724413 XP_006724476 XM_011530682 XP_011528984 XM_011530683 XP_011528985 XM_011530684 XP_011528986 NM_012401 NP_036533
Function Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. Regulates the migration of cerebellar granule cells in the developing brain. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May modulate the activity of RAC1 and CDC42. Down-regulates macrophage migration in wound- healing assays (in vitro) (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:12533544}; Single-pass type I membrane protein {ECO:0000269|PubMed:12533544}.
Top Pathways Axon guidance

Plexin B2 (PLXNB2), ELISA Kit - MBS9303988 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Plexin-B2, ELISA Kit - MBS280803 from MyBioSource

Category ELISA Kit
Prices $425.00, $720.00, $3,160.00, $6,055.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Custom Human Plexin B2 ELISA - ELH-PLXB2 from RayBiotech

Category ELISA Kit
Prices $615.00, $1,107.00, $2,460.00
Sizes 1 plate kit, 2 plate kit, 5 plate kit

Custom Human Plexin B2 Elisa kit - orb305371 from Biorbyt

Category ELISA Kit
Prices $1,148.00, $1,981.00, $4,284.00
Sizes 96 assays, 192 assays, 480 assays

Human Plexin B2 ELISA - RAB1638 from Sigma-Aldrich

Prices $615.00
Sizes 1 kt

Custom Human Plexin B2 ELISA - ELH-PLXB2-1 from RayBiotech

Category ELISA Kit
Prices $615.00, $1,107.00, $2,460.00
Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human PLXNB2 ELISA Kit - E029885 from Biobool

Category ELISA Kit
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