PLXNB2

Gene Symbol PLXNB2
Entrez Gene 23654
Alt Symbol MM1, Nbla00445, PLEXB2, dJ402G11.3
Species Human
Gene Type protein-coding
Description plexin B2
Other Description plexin-B2
Swissprots Q9BSU7 O15031 Q7KZU3 A6QRH0
Accessions CCF76956 O15031 AB002313 BAA21571 AB075511 BAE45757 AK025415 AK025701 AK056543 AK074932 AK123131 AK126394 BC000221 BC004542 AAH04542 BC110366 AAI10367 BC127770 AAI27771 BC148225 BC148280 BC172440 AAI72440 BT006887 AAP35533 CN388620 S76730 AAB33781 XM_005261909 XP_005261966 XM_005261910 XP_005261967 XM_005261911 XP_005261968 XM_006724413 XP_006724476 XM_011530682 XP_011528984 XM_011530683 XP_011528985 XM_011530684 XP_011528986 NM_012401 NP_036533
Function Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. Regulates the migration of cerebellar granule cells in the developing brain. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May modulate the activity of RAC1 and CDC42. Down-regulates macrophage migration in wound- healing assays (in vitro) (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:12533544}; Single-pass type I membrane protein {ECO:0000269|PubMed:12533544}.
Top Pathways Axon guidance

plexin-B2 (A-5) - sc-373969 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
plexin-B2 (A-5): sc-373969. Western blot analysis of plexin-B2 expression in 293T whole cell lysate (A) and mouse brain tissue extract (B).

plexin-B2 (H-12) - sc-373930 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
plexin-B2 (H-12): sc-373930. Western blot analysis of plexin-B2 expression in non-transfected: sc-117752 (A) and mouse plexin-B2 transfected: sc-122643 (B) 293T whole cell lysates.

plexin-B2 (H-90) - sc-67034 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
plexin-B2 (H-90): sc-67034. Western blot analysis of plexin-B2 expression in mouse brain tissue extract.

plexin-B2 (I-16) - sc-34504 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
plexin-B2 (I-16): sc-34504. Western blot analysis of plexin-B2 expression in non-transfected: sc-117752 (A) and mouse plexin-B2 transfected: sc-122643 (B) 293T whole cell lysates.

plexin-B2 (N-16) - sc-34506 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

plexin-B2 (P-16) - sc-34507 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Plexin B2 antibody [EPR9965] - ab193355 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9965
Anti-Plexin B2 antibody [EPR9965] (ab193355) at 1/10000 dilution + HeLa cell lysate at 20 µgSecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-Plexin B2 antibody [MM0876-9P44] - ab201635 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0876-9P44

Anti-PLXNB2 / Plexin B2 Antibody (clone 3E7, Biotin) - LS-C106207 from LifeSpan Bioscience

Prices $245.00, $315.00, $495.00
Sizes 50 µg, 100 µg, 500 µg
Host Hamster
Clonality Monoclonal
Clone 3E7
Staining of BALB/c splenocytes with FITC anti-mo/hu B220 (RA3-6B2) (LS-C105879) and Biotin anti-mouse Plexin-B2 (3E7). Total viable cells were used for analysis.

Anti-PLXNB2 / Plexin B2 Antibody (clone 3E7) - LS-C106872 from LifeSpan Bioscience

Prices $245.00, $305.00, $455.00
Sizes 50 µg, 100 µg, 500 µg
Host Hamster
Clonality Monoclonal
Clone 3E7
Staining of the PDV cell line with 0.25 ug of Purified Armenian Hamster IgG isotype control (open histogram) or 0.25 ug of Purified anti-mouse Plexin-B2 (3E7) (colored histogram) followed by Biotin Anti-Armenian Hamster IgG and SAv-PE. Total viable cells were used for analysis.

Anti-PLXNB2 / Plexin B2 Antibody (clone 3E7, PE) - LS-C106111 from LifeSpan Bioscience

Prices $255.00, $335.00, $425.00
Sizes 50 µg, 100 µg, 200 µg
Host Hamster
Clonality Monoclonal
Clone 3E7
Staining of C57Bl/6 splenocytes with APC anti-mo/hu B220 (RA3-6B2) (LS-C107315) and 0.125 ug of PE anti-mouse Plexin-B2 (right). Total viable cells were used for analysis.

Plexin B2 Antibody - AF5329 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Western blot shows lysates of human brain tissue. PVDF membrane was probed with 1 µg/mL of Sheep Anti-Human Plexin B2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5329) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for Plexin B2 at approximately 170 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8.

Plexin B2 Antibody (537237) - MAB5329 from Novus Biologicals

Prices $99.00, $259.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 537237
Plexin B2 was detected in immersion fixed paraffin-embedded sections of human colon using Mouse Anti-Human Plexin B2 Monoclonal Antibody (Catalog # MAB5329) at 15 µg/mL overnight at 4 °C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counterstained with hematoxylin (blue). Specific staining was localized to brush border in epithelial cells. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

Plexin B2 Antibody (537219) - MAB53292 from Novus Biologicals

Prices $249.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 537219
Western Blot Plexin B2 Antibody (537219)

Plexin B2 Antibody - NBP1-89620 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Plexin B2 Antibody [NBP1-89620] - Staining of human skeletal muscle shows distinct cytoplasmic positivity in myocytes.

Plexin B2 Antibody (2H3) - H00023654-M07 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2H3
Western Blot: Plexin B2 Antibody (2H3) [H00023654-M07] - Analysis of PLXNB2 expression in transfected 293T cell line by PLXNB2 monoclonal antibody (M07), clone 2H3. Lane 1: PLXNB2 transfected lysate (Predicted MW: 205.1 KDa). Lane 2: Non-transfected lysate.

Plexin B2 Antibody - H00023654-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Plexin B2 Antibody [Biotin] - BAF5329 from Novus Biologicals

Prices $390.00
Sizes 50 µg
Host Sheep
Clonality Polyclonal

Plexin B2 Antibody (537223) [Phycoerythrin] - FAB53291P from Novus Biologicals

Prices $299.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 537223
Human peripheral blood monocytes were stained with Mouse Anti-Human Plexin B2 PE‑conjugated Monoclonal Antibody (Catalog # FAB53291P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). View our protocol for Staining Membrane-associated Proteins.

Plexin B2 Antibody (537223) [Allophycocyanin] - FAB53291A from Novus Biologicals

Prices $339.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 537223
Whole blood monocytes were stained with Mouse Anti-Human Plexin B2 APC‑conjugated Monoclonal Antibody (Catalog # FAB53291A, filled histogram) or isotype control antibody (Catalog # IC003A, open histogram). View our protocol for Staining Membrane-associated Proteins.

Plexin B2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11215R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Plexin B2 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11215R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Plexin B2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11215R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Plexin B2 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11215R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Plexin B2 Polyclonal Antibody, Cy3 Conjugated - bs-11215R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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