PLXNB2

Gene Symbol	PLXNB2
Entrez Gene	23654
Alt Symbol	MM1, Nbla00445, PLEXB2, dJ402G11.3
Species	Human
Gene Type	protein-coding
Description	plexin B2
Other Description	plexin-B2
Swissprots	Q9BSU7 O15031 Q7KZU3 A6QRH0
Accessions	CCF76956 O15031 AB002313 BAA21571 AB075511 BAE45757 AK025415 AK025701 AK056543 AK074932 AK123131 AK126394 BC000221 BC004542 AAH04542 BC110366 AAI10367 BC127770 AAI27771 BC148225 BC148280 BC172440 AAI72440 BT006887 AAP35533 CN388620 S76730 AAB33781 XM_005261909 XP_005261966 XM_005261910 XP_005261967 XM_005261911 XP_005261968 XM_006724413 XP_006724476 XM_011530682 XP_011528984 XM_011530683 XP_011528985 XM_011530684 XP_011528986 NM_012401 NP_036533
Function	Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. Regulates the migration of cerebellar granule cells in the developing brain. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May modulate the activity of RAC1 and CDC42. Down-regulates macrophage migration in wound- healing assays (in vitro) (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:12533544}; Single-pass type I membrane protein {ECO:0000269|PubMed:12533544}.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

Human Plexin B2 protein fragment - ab132461 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human Plexin B2 Protein - H00023654-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Plexin B2 Protein - H00023654-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Plexin B2, CF - 5329-PB-050 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, Leu20-Arg1160, with a C-terminal 6-His tag

Plexin B2 - H00023654-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Plexin B2 - H00023654-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Plexin B2 - H00023654-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Plexin B2 - H00023654-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

PLXNB2 fusion protein - ag0941 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human PLXNB2, His-tagged - PLXNB2-30906TH from Creative Biomart Category Protein Source E. coli

Recombinant Human PLXNB2 - PLXNB2-690H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Human PLXNB2, His-tagged - PLXNB2-931H from Creative Biomart Category Protein Source CHO Cells Species Human

Recombinant Human Plexin-B2(PLXNB2) ,partial - CSB-YP018223HU CSB-EP018223HU CSB-BP018223HU CSB-MP018223HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Plexin B2 Protein, CF - 5329-PB from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Chinese Hamster Ovary cell line, CHO-derived Leu20-Arg1160, with a C-terminal 6-His tag Species Human

Plexin-B2 (PLXNB2), partial, Recombinant Protein - MBS1212472 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Plexin B2 Protein - NBP1-89620PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

PLXNB2 Peptide, Human - M34GP11991H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Mouse Plexin B2 Protein, CF - 6836-PB from Novus Biologicals Category Protein Prices $329.00 Sizes 50 µg

Search more