PGAM5

Gene Symbol PGAM5
Entrez Gene 192111
Alt Symbol BXLBV68
Species Human
Gene Type protein-coding
Description phosphoglycerate mutase family member 5
Other Description Bcl-XL-binding protein v68|serine/threonine-protein phosphatase PGAM5, mitochondrial
Swissprots A9LN06 C9IZY7 Q96JB0 Q96HS1
Accessions EAW54825 EAW54826 EAW54827 Q96HS1 AF357523 AAK60627 AK097688 BC008196 AAH08196 BC047906 CA307621 CR995429 D25830 DR155760 EU249757 ABX39494 NM_001170543 NP_001164014 NM_001170544 NP_001164015 NM_138575 NP_612642
Function Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2- dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore. {ECO:0000269|PubMed:18387606, ECO:0000269|PubMed:19590015, ECO:0000269|PubMed:22265414}.
Subcellular Location Mitochondrion outer membrane {ECO:0000269|PubMed:18387606}; Single-pass membrane protein {ECO:0000269|PubMed:18387606}. Note=Isoform 2 overexpression results in the formation of disconnected punctuate mitochondria distributed throughout the cytoplasm. Isoform 1 overexpression results in the clustering of mitochondria around the nucleus.
Top Pathways TNF signaling pathway

phosphoglycerate mutase family member 5, ELISA Kit - MBS9322387 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.1ng/ml.
Range 0.625 ng/ml - 20 ng/ml.

Human PGAM5 ELISA Kit - E093337 from Biobool

Category ELISA Kit

Human Serine/threonine-protein phosphatase PGAM5, mitochondrial (PGAM5) ELISA Kit - AE27853HU from ARP American Research Products

Category ELISA Kit
Prices $549.00
Sizes 96 t
Sensitivity 0.057 ng/mL
Range 0.156-10 ng/mL

Serine/Threonine-Protein Phosphatase PGAM5, Mitochondrial (PGAM5), ELISA Kit - MBS9346575 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Phosphatase PGAM5, Mitochondrial (PGAM5), ELISA Kit - MBS9348541 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Phosphatase PGAM5, Mitochondrial (PGAM5), ELISA Kit - MBS9364550 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Phosphatase PGAM5, Mitochondrial (PGAM5), ELISA Kit - MBS9350473 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Phosphatase PGAM5, Mitochondrial (PGAM5), ELISA Kit - MBS9358650 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Phosphatase PGAM5, Mitochondrial (PGAM5), ELISA Kit - MBS9352237 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Phosphatase PGAM5, Mitochondrial (PGAM5), ELISA Kit - MBS9343663 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Phosphatase PGAM5, Mitochondrial (PGAM5), ELISA Kit - MBS9367428 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Phosphatase PGAM5, Mitochondrial (PGAM5), ELISA Kit - MBS9368871 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Phosphatase PGAM5, Mitochondrial (PGAM5), ELISA Kit - MBS9347780 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Phosphatase PGAM5, Mitochondrial (PGAM5), ELISA Kit - MBS9354238 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Phosphatase PGAM5, Mitochondrial (PGAM5), ELISA Kit - MBS9370149 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Phosphatase PGAM5, Mitochondrial (PGAM5), ELISA Kit - MBS9346462 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Phosphatase PGAM5, Mitochondrial (PGAM5), ELISA Kit - MBS9364433 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Phosphatase PGAM5, Mitochondrial (PGAM5), ELISA Kit - MBS9357629 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Phosphatase PGAM5, Mitochondrial (PGAM5), ELISA Kit - MBS9355320 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Phosphatase PGAM5, Mitochondrial (PGAM5), ELISA Kit - MBS9350408 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Phosphatase PGAM5, Mitochondrial (PGAM5), ELISA Kit - MBS9368681 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Phosphatase PGAM5, Mitochondrial (PGAM5), ELISA Kit - MBS9365436 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Serine/Threonine-Protein Phosphatase PGAM5, Mitochondrial (PGAM5), ELISA Kit - MBS9358129 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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