CDK3

Gene Symbol CDK3
Entrez Gene 1018
Alt Symbol -
Species Human
Gene Type protein-coding
Description cyclin-dependent kinase 3
Other Description cell division protein kinase 3
Swissprots Q00526
Accessions AAV40830 EAW89353 EAW89354 EAW89355 Q00526 AU146328 BC128406 BC160074 AAI60074 BU784937 BX098771 DB455174 X66357 CAA47001 NM_001258 NP_001249
Function Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0- G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1- independent manner. {ECO:0000269|PubMed:15084261, ECO:0000269|PubMed:18794154, ECO:0000269|PubMed:8846921}.
Tissue Specificity Expressed in cancer cell lines and glioblastoma tissue. {ECO:0000269|PubMed:18794154}.

Cdk3 (S-13) - sc-32499 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Cdk3 (S-13): sc-32499. Western blot analysis of Cdk3 expression in MCF7 whole cell lysate.

Cdk3 (H-45) - sc-28256 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Cdk3 (H-45): sc-28256. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.

Cdk3 (Y-20) - sc-826 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Cdk3 (R-11) - sc-32498 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Cdk3 (K-11) - sc-32500 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Cdk3 (4B6) - sc-81836 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Cdk3 (4B6): sc-81836. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human testis tissue showing nuclear localization.

Anti-Cdk3 antibody - ab191503 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cdk3 antibody (ab191503)Lane 1 : HEK293T whole cell lysateLane 2 : Raw264.7 whole cell lysateLane 3 : PC12 whole cell lysate

Anti-Cdk3 antibody - ab54514 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Cdk3 antibody (ab54514) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human testis.

Anti-Cdk3 antibody - ab116392 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Cdk3 antibody (ab116392) at 1/100 dilution + CEM cell line lysates at 35 µg

Anti-Cdk3 antibody - ab96847 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Cdk3 antibody (ab96847) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

Anti-Cdk3 antibody - N-terminal - ab135805 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cdk3 antibody - N-terminal (ab135805) at 1/50 dilutionLane 1 : 293 cell lysates, non-transfectedLane 2 : 293 cell lysates transiently transfected with the Cdk3 gene Lysates/proteins at 2 µg per lane.

Anti-CDK3 Antibody (aa248-277, AP) - LS-C254424 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDK3 Antibody (aa248-277, Azide-free, HRP) - LS-C254426 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDK3 Antibody (aa248-277, APC) - LS-C254425 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDK3 Antibody (aa248-277, Biotin) - LS-C254428 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDK3 Antibody (aa248-277, FITC) - LS-C254427 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDK3 Antibody (aa248-277, PE) - LS-C254431 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDK3 Antibody - LS-C309858 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CDK3 Antibody (aa1-238) - LS-C185680 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate). A: Hep G2 . 10% SDS PAGE. Cdk3 antibody. CDK3 antibody diluted at 1:1000.

Anti-CDK3 Antibody (aa248-277) - LS-C320265 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDK3 Antibody - LS-C340925 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CDK3 Antibody (C-Terminus) - LS-C82026 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-CDK3 Antibody (N-Terminus) - LS-C345775 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of CDK3 Antibody with human 293T Whole Cell lysate.

Anti-CDK3 Antibody (clone 3C12) - LS-C104915 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3C12
Western blot of CDK3 expression in transfected 293T cell line by CDK3 monoclonal antibody (M01), clone 3C12.

Anti-CDK3 Antibody (aa14-43) - LS-C168613 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human lung carcinoma reacted with CDK3 Antibody (N-term Y19), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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