CDK3

Gene Symbol CDK3
Entrez Gene 1018
Alt Symbol -
Species Human
Gene Type protein-coding
Description cyclin-dependent kinase 3
Other Description cell division protein kinase 3
Swissprots Q00526
Accessions AAV40830 EAW89353 EAW89354 EAW89355 Q00526 AU146328 BC128406 BC160074 AAI60074 BU784937 BX098771 DB455174 X66357 CAA47001 NM_001258 NP_001249
Function Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0- G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1- independent manner. {ECO:0000269|PubMed:15084261, ECO:0000269|PubMed:18794154, ECO:0000269|PubMed:8846921}.
Tissue Specificity Expressed in cancer cell lines and glioblastoma tissue. {ECO:0000269|PubMed:18794154}.

CDK3-Over-expression-Lysate - LY10026a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag CDK3 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CDK3 gene (Lane 2, Cat. #LY10026a).

CDK3 overexpression lysate - LY420045 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

Cdk3 Overexpression Lysate (Denatured) - H00001018-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Panoply™ Human CDK3 Knockdown Stable Cell Line - CSC-DC002873 from Creative biogene

Category Cell Line
Species Human

CDK3 Knockout Cell Line-HeLa - CSC-RT1851 from Creative biogene

Category Cell Line
Species Human

CDK3 KO Cell Lysate-HeLa - CLKO-1700 from Creative biogene

Category Cell Lysate
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