CDK3

Gene Symbol	CDK3
Entrez Gene	1018
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	cyclin-dependent kinase 3
Other Description	cell division protein kinase 3
Swissprots	Q00526
Accessions	AAV40830 EAW89353 EAW89354 EAW89355 Q00526 AU146328 BC128406 BC160074 AAI60074 BU784937 BX098771 DB455174 X66357 CAA47001 NM_001258 NP_001249
Function	Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0- G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1- independent manner. {ECO:0000269|PubMed:15084261, ECO:0000269|PubMed:18794154, ECO:0000269|PubMed:8846921}.
Tissue Specificity	Expressed in cancer cell lines and glioblastoma tissue. {ECO:0000269|PubMed:18794154}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CDK3 Gene ORF cDNA clone in cloning vector - HG10891-M from Sino Biological Species Human

Human CDK3 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10891-NF from Sino Biological Species Human

Human CDK3 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10891-NM from Sino Biological Species Human

Human CDK3 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10891-CY from Sino Biological Species Human

Human CDK3 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10891-CF from Sino Biological Species Human

Human CDK3 Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-tagged - HG10891-M-F from Sino Biological Species Human Accession NM_001258.2

Human CDK3 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG10891-M-N from Sino Biological Species Human Accession NM_001258.2

Human CDK3 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10891-CM from Sino Biological Species Human

Human CDK3 Gene ORF cDNA clone expression plasmid, N-His tag - HG10891-NH from Sino Biological Species Human

Human CDK3 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10891-NY from Sino Biological Species Human

Human CDK3 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG10891-ANG from Sino Biological Species Human

Human CDK3 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10891-ACR from Sino Biological Species Human

Human CDK3 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG10891-ANR from Sino Biological Species Human

Human CDK3 Gene ORF cDNA clone expression plasmid, C-His tag - HG10891-CH from Sino Biological Species Human

Human CDK3 Gene ORF cDNA clone expression plasmid - HG10891-UT from Sino Biological Species Human

Human CDK3 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10891-ACG from Sino Biological Species Human

Human CDK3 ORF clone(NM_001258.2) - CDCL183499 from Creative biogene Species Human

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