CDK3

Gene Symbol	CDK3
Entrez Gene	1018
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	cyclin-dependent kinase 3
Other Description	cell division protein kinase 3
Swissprots	Q00526
Accessions	AAV40830 EAW89353 EAW89354 EAW89355 Q00526 AU146328 BC128406 BC160074 AAI60074 BU784937 BX098771 DB455174 X66357 CAA47001 NM_001258 NP_001249
Function	Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0- G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1- independent manner. {ECO:0000269|PubMed:15084261, ECO:0000269|PubMed:18794154, ECO:0000269|PubMed:8846921}.
Tissue Specificity	Expressed in cancer cell lines and glioblastoma tissue. {ECO:0000269|PubMed:18794154}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Cyclin E1 + Cdk3 full length protein - ab196131 from Abcam Category Protein Prices $710.00 Sizes 10 µg Source Baculovirus infected sf9 cells Species Human

Human Cdk3 full length protein - ab126928 from Abcam Category Protein Prices $235.00 Sizes 20 µg Source Baculovirus infected sf9 cells Species Human

Human Cdk3 full length protein - ab158081 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human Cdk3 full length protein - ab167912 from Abcam Category Protein Prices $297.00 Sizes 50 µg Source E. coli Species Human

Human Cdk3 protein fragment - ab158082 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

CDK3 Antibody Blocking Peptide - LS-E2718 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CDK3 Antibody Blocking Peptide - LS-E10492 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CDK3 Antibody Blocking Peptide - LS-E9022 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Cdk3 Recombinant Protein - H00001018-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Cdk3 Partial Recombinant Protein - H00001018-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Cdk3 Protein - NBP2-22973 from Novus Biologicals Category Protein Prices $269.00 Sizes 50 µg Source E.coli Species Human

CDK3-Antibody-N-term-Y19-Blocking-Peptide - BP7519a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human CDK3 Enzyme - orb191434 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source Escherichia Coli. Species Human

CDK3 Blocking Peptide - 33R-6756 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CDK3 protein (His tag) - 80R-2874 from Fitzgerald Category Protein Prices $275.00 Sizes 50 µg Source E.coli

CDK3 Blocking Peptide - abx064137 from Abbexa Category Peptide Species Human, Mouse, Rat

CDK3 (1-305, His-tag) - AR50993PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

CDK3 (1-305, His-tag) - AR50993PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

CDK3 - H00001018-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CDK3 - H00001018-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CDK3 - H00001018-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CDK3 - H00001018-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CDK3 - P4656 from Acris Antibodies Category Protein Prices $1,380.00 Sizes 100 µg Species Human

CDK3 - P5513 from Acris Antibodies Category Protein Prices $840.00 Sizes 5 µg Species Human

CDK3, 1-305aa, Human, His tag, E.coli - 01-P2169 from ARP American Research Products Category Protein Prices $149.00, $369.00, $849.00 Sizes 10 µg, 50 µg, 250 µg Species Human

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