DIS3L

Gene Symbol DIS3L
Entrez Gene 115752
Alt Symbol DIS3L1
Species Human
Gene Type protein-coding
Description DIS3 like exosome 3'-5' exoribonuclease
Other Description DIS3 mitotic control homolog-like|DIS3-like exonuclease 1
Swissprots Q96CM7 Q8N1N8 Q8TF46 Q8WTU9
Accessions CCQ43824 EAW77758 EAW77759 EAW77760 EAW77761 Q8TF46 AB075835 BAB85541 AF147431 AK095407 BAC04542 AK123202 AK295392 BAG58346 BC014124 AAH14124 BC022089 AAH22089 BG722405 BM833083 BP219623 DQ893470 ABM84396 EU176766 ABW03567 NM_001143688 NP_001137160 XM_005254144 XP_005254201 XM_005254145 XP_005254202 XM_005254146 XP_005254203 XM_005254147 XP_005254204 NM_133375 NP_588616
Function Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. {ECO:0000269|PubMed:20531386, ECO:0000269|PubMed:20531389}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:20531386, ECO:0000269|PubMed:20531389}.
Top Pathways RNA degradation

DIS3L (E-12) - sc-398739 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DIS3L (E-12): sc-398739. Western blot analysis of DIS3L expression in T98G (A), SCC-4 (B) and HeLa (C) whole cell lysates.

DIS3L (D-15) - sc-242581 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

DIS3L (H-110) - sc-368891 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

DIS3L (W-18) - sc-242579 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-DIS3L antibody - ab89042 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-DIS3L antibody (ab89042) at 1 µg/ml + Human liver tissue lysate at 50 µg

Anti-DIS3L Antibody (aa195-224, AP) - LS-C256105 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DIS3L Antibody (aa195-224, Azide-free, HRP) - LS-C256109 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DIS3L Antibody (aa195-224) - LS-C167411 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
DI3L1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human cervix carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-DIS3L Antibody (aa195-224, PE) - LS-C256110 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DIS3L Antibody (aa202-232) - LS-C320841 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DIS3L Antibody - LS-C308996 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-DIS3L Antibody (aa195-224, APC) - LS-C256106 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DIS3L Antibody (aa195-224, Biotin) - LS-C256107 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DIS3L Antibody (aa195-224, FITC) - LS-C256108 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

DIS3L Antibody - H00115752-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

DIS3L Antibody - NBP1-81941 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: DIS3L Antibody [NBP1-81941] - Staining of human cell line U-251 MG shows positivity in plasma membrane, cytoplasm & centrosome.

DIS3L Polyclonal Antibody - bs-9052R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MGC4562 antibody produced in mouse - SAB1400782 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-MGC4562, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1400782</B>: Antibody concentration: 1.0 ~ 5.0 μg/mL. Specific band of ~111.1 kDa using human liver lysate.

Anti-DIS3L antibody produced in rabbit - HPA041805 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-DIS3L: <B>Cat. No. HPA041805</B>: Immunohistochemical staining of human kidney shows moderate cytoplasmic positivity in cells in tubules.

ANTI-DI3L1 (N-TERMINAL) antibody produced in rabbit - SAB1306324 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-DI3L1 (N-term): <B>Cat. No. SAB1306324</B>: DI3L1 Antibody (N-term) western blot analysis in Mouse heart tissue lysates (15 μg/lane).

DIS3L Antibody - N-terminal region (OAAB03025) - OAAB03025 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

DI3L1-Antibody-N-term - AP5614a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
DI3L1 Antibody (N-term) (Cat. #AP5614a) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the DI3L1 antibody detected DI3L1 protein (arrow).

Anti -DI3L1, NT (DIS3L, DIS3L1, KIAA1955, DIS3-like exonuclease 1) - 034639 from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -DI3L1, NT (DIS3L, DIS3L1, KIAA1955, DIS3-like exonuclease 1) (AP) - 034639-AP from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -DI3L1, NT (DIS3L, DIS3L1, KIAA1955, DIS3-like exonuclease 1) (APC) - 034639-APC from USBiological Life Science

Host Rabbit
Clonality Polyclonal
Search more