DIS3L

Gene Symbol	DIS3L
Entrez Gene	115752
Alt Symbol	DIS3L1
Species	Human
Gene Type	protein-coding
Description	DIS3 like exosome 3'-5' exoribonuclease
Other Description	DIS3 mitotic control homolog-like|DIS3-like exonuclease 1
Swissprots	Q96CM7 Q8N1N8 Q8TF46 Q8WTU9
Accessions	CCQ43824 EAW77758 EAW77759 EAW77760 EAW77761 Q8TF46 AB075835 BAB85541 AF147431 AK095407 BAC04542 AK123202 AK295392 BAG58346 BC014124 AAH14124 BC022089 AAH22089 BG722405 BM833083 BP219623 DQ893470 ABM84396 EU176766 ABW03567 NM_001143688 NP_001137160 XM_005254144 XP_005254201 XM_005254145 XP_005254202 XM_005254146 XP_005254203 XM_005254147 XP_005254204 NM_133375 NP_588616
Function	Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. {ECO:0000269|PubMed:20531386, ECO:0000269|PubMed:20531389}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:20531386, ECO:0000269|PubMed:20531389}.
Top Pathways	RNA degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

DIS3L - MBS1269095 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC022089

Human DIS3L cDNA clone(NM_001143688.1) - CDFH005094 from Creative Biomart Species Human Accession NM_001143688.1

Human DIS3L ORF Clone(NM_001143688.1) - CDCR351765 from Creative Biomart Species Human Accession NM_001143688.1

Human DIS3L ORF Clone(NM_001143688.1) - CDCR351771 from Creative Biomart Species Human Accession NM_001143688.1

Human DIS3L ORF Clone(NM_001143688.1) - CDCL161098 from Creative Biomart Species Human Accession NM_001143688.1

Human DIS3L Gene ORF cDNA clone in cloning vector - HG14378-G from Sino Biological Species Human

Human DIS3L Gene ORF cDNA clone expression plasmid, C-HA tag - HG14378-CY from Sino Biological Species Human

Human DIS3L Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14378-NF from Sino Biological Species Human

Human DIS3L Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14378-CF from Sino Biological Species Human

Human DIS3L Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14378-NM from Sino Biological Species Human

Human DIS3L Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14378-CM from Sino Biological Species Human

Human DIS3L Gene ORF cDNA clone expression plasmid, N-His tag - HG14378-NH from Sino Biological Species Human

Human DIS3L Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG14378-ANG from Sino Biological Species Human

Human DIS3L Gene ORF cDNA clone expression plasmid, N-HA tag - HG14378-NY from Sino Biological Species Human

Human DIS3L Gene ORF cDNA clone expression plasmid, C-His tag - HG14378-CH from Sino Biological Species Human

Human DIS3L Gene ORF cDNA clone expression plasmid - HG14378-UT from Sino Biological Species Human

Human DIS3L ORF clone (NM_001143688.1) - CDCR055678 from Creative biogene Species Human

Human DIS3L ORF Clone (BC022089) - CDCS408338 from Creative biogene Species Human Accession Q8TF46

Human DIS3L ORF clone (BC022089) - CDCB159125 from Creative biogene Species Human

Human DIS3L cDNA Clone(NM_001143688.1) - CDFH005094 from Creative biogene Species Human

Human DIS3L Gene cDNA Clone - orb142865 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Human DIS3L Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14378-ACR from Sino Biological Species Human

Human DIS3L Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG14378-ANR from Sino Biological Species Human

Human DIS3L Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14378-ACG from Sino Biological Species Human

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