DIS3L

Gene Symbol	DIS3L
Entrez Gene	115752
Alt Symbol	DIS3L1
Species	Human
Gene Type	protein-coding
Description	DIS3 like exosome 3'-5' exoribonuclease
Other Description	DIS3 mitotic control homolog-like|DIS3-like exonuclease 1
Swissprots	Q96CM7 Q8N1N8 Q8TF46 Q8WTU9
Accessions	CCQ43824 EAW77758 EAW77759 EAW77760 EAW77761 Q8TF46 AB075835 BAB85541 AF147431 AK095407 BAC04542 AK123202 AK295392 BAG58346 BC014124 AAH14124 BC022089 AAH22089 BG722405 BM833083 BP219623 DQ893470 ABM84396 EU176766 ABW03567 NM_001143688 NP_001137160 XM_005254144 XP_005254201 XM_005254145 XP_005254202 XM_005254146 XP_005254203 XM_005254147 XP_005254204 NM_133375 NP_588616
Function	Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. {ECO:0000269|PubMed:20531386, ECO:0000269|PubMed:20531389}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:20531386, ECO:0000269|PubMed:20531389}.
Top Pathways	RNA degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DIS3L full length protein - ab165081 from Abcam Category Protein Source Wheat germ Species Human

DIS3L Antibody Blocking Peptide - LS-E7906 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human DIS3L Protein - H00115752-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

DI3L1-Antibody-N-term-Blocking-peptide - BP5614a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DIS3-like exonuclease 1 - H00115752-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

DIS3-like exonuclease 1 - H00115752-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

DIS3L fusion protein - Ag22689 from Proteintech Group Category Protein Prices $199.00 Sizes 50 Source E. coli -derived, PET28a Species Human

Recombinant Human DIS3-like exonuclease 1(DIS3L) ,partial - CSB-YP823476HU CSB-EP823476HU CSB-BP823476HU CSB-MP823476HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

DIS3-like exonuclease 1 (transcript variant 2) - TP301404 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

DIS3L Recombinant Protein Antigen - NBP1-81941PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

DIS3L Peptide, Human - M34GP04320H from Creative Peptides Category Peptide Source Synthetic. Species Human

DIS3-like exonuclease 1 (DIS3L), partial, Recombinant Protein - MBS1324159 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Search more