MEOX1

Gene Symbol	MEOX1
Entrez Gene	4222
Alt Symbol	KFS2, MOX1
Species	Human
Gene Type	protein-coding
Description	mesenchyme homeobox 1
Other Description	homeobox protein MOX-1
Swissprots	A8MWF9 P50221 A8K524 Q15069
Accessions	EAW51671 EAW51672 P50221 AK291139 BAF83828 AW410297 BC069474 AAH69474 BC069506 AAH69506 BE898972 BG677020 BQ003431 BQ028272 BX284090 EU446636 ABZ92165 U10492 AAA19983 U10493 AAA19984 XM_011524818 XP_011523120 NM_001040002 NP_001035091 NM_004527 NP_004518 NM_013999 NP_054705
Function	Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints (PubMed:23290072, PubMed:24073994). Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome. {ECO:0000250|UniProtKB:F1Q4R9, ECO:0000250|UniProtKB:P32442, ECO:0000269|PubMed:23290072, ECO:0000269|PubMed:24073994}.
Subcellular Location	Nucleus {ECO:0000250|UniProtKB:P32442}. Cytoplasm {ECO:0000250|UniProtKB:P32442}. Note=Localizes predominantly in the nucleus. {ECO:0000250|UniProtKB:P32442}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MEOX1-Over-expression-Lysate - LY11922a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

MEOX1 293T Cell Transient Overexpression Lysate(Denatured) - H00004222-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

MEOX1 overexpression lysate - LY417902 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

MEOX1 overexpression lysate - LY421872 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

MEOX1 overexpression lysate - LY425669 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

MEOX1 293 Cell Lysate - 408373 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

MOX1 Overexpression Lysate (Denatured) - H00004222-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

MOX1 Overexpression Lysate (Native) - NBL1-13009 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

MEOX1 Over-expression Lysate Product - GWB-3829B5 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

MOX1 Overexpression Lysate (Native) - NBP2-10626 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

MOX1 Overexpression Lysate (Native) - NBP2-11202 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Panoply™ Human MEOX1 Knockdown Stable Cell Line - CSC-DC009403 from Creative biogene Category Cell Line Species Human

Human MEOX1 Knockout Cell Line-HeLa - CSC-RT1539 from Creative biogene Category Cell Line Species Human

MEOX1 KO Cell Lysate-HeLa - CLKO-1386 from Creative biogene Category Cell Lysate

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