MEOX1

Gene Symbol	MEOX1
Entrez Gene	4222
Alt Symbol	KFS2, MOX1
Species	Human
Gene Type	protein-coding
Description	mesenchyme homeobox 1
Other Description	homeobox protein MOX-1
Swissprots	A8MWF9 P50221 A8K524 Q15069
Accessions	EAW51671 EAW51672 P50221 AK291139 BAF83828 AW410297 BC069474 AAH69474 BC069506 AAH69506 BE898972 BG677020 BQ003431 BQ028272 BX284090 EU446636 ABZ92165 U10492 AAA19983 U10493 AAA19984 XM_011524818 XP_011523120 NM_001040002 NP_001035091 NM_004527 NP_004518 NM_013999 NP_054705
Function	Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints (PubMed:23290072, PubMed:24073994). Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome. {ECO:0000250|UniProtKB:F1Q4R9, ECO:0000250|UniProtKB:P32442, ECO:0000269|PubMed:23290072, ECO:0000269|PubMed:24073994}.
Subcellular Location	Nucleus {ECO:0000250|UniProtKB:P32442}. Cytoplasm {ECO:0000250|UniProtKB:P32442}. Note=Localizes predominantly in the nucleus. {ECO:0000250|UniProtKB:P32442}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MOX1 full length protein - ab132276 from Abcam Category Protein Source Wheat germ Species Human

Human MOX1 protein fragment - ab114872 from Abcam Category Protein Source Wheat germ Species Human

Human MOX1 protein fragment - ab152529 from Abcam Category Protein Source Wheat germ Species Human

MOX1 peptide - ab199249 from Abcam Category Peptide

MOX1 peptide - ab199250 from Abcam Category Peptide

MEOX1 Antibody Blocking Peptide - LS-E3392 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MEOX1 Antibody Blocking Peptide - LS-E31009 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human MOX1 Protein - H00004222-Q02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human MOX1 Protein - H00004222-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MOX1 Partial Protein - H00004222-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MOX1 Blocking Peptide - NBP1-76302PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

MEOX1-Antibody-Center-Blocking-Peptide - BP14566c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MEOX1 - H00004222-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MEOX1 - H00004222-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MEOX1 - H00004222-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MEOX1 - H00004222-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MEOX1 - H00004222-Q02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

MEOX1 - H00004222-Q02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MEOX1 - H00004222-Q02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MEOX1 control peptide - AP26278CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

MOX1 Peptide - 5995P from ProSci Category Peptide Species Human

MEOX1 fusion protein - ag12925 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

MEOX1 fusion protein - ag12910 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human MEOX1 - MEOX1-29355TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human Homeobox protein MOX-1(MEOX1) - CSB-YP013695HU CSB-EP013695HU CSB-BP013695HU CSB-MP013695HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Search more